List I List II A. TLR 3 I. Lipopolysaccharide B. TLR 4 II. Double stranded RNA C. TLR 5 III. Flagellin D. TLR 7 IV. Single stranded RNA
Choose the correct answer from the options given below:
TLR Receptor Ligand Matching Explained
This solution explains the correct matching between Toll-Like Receptors (TLRs) in List I and their specific molecular triggers (ligands) in List II.
TLR 3 Recognition
TLR 3 is known to detect viral genetic material, specifically Double-stranded RNA (dsRNA). Therefore, A corresponds to II.
TLR 4 Recognition
TLR 4 is a key receptor for identifying Gram-negative bacteria, recognizing the molecule Lipopolysaccharide (LPS). Thus, B corresponds to I.
TLR 5 Recognition
TLR 5 recognizes structural components of motile bacteria, namely Flagellin, the protein found in bacterial flagella. This means C corresponds to III.
TLR 7 Recognition
TLR 7 is involved in sensing viral infections by detecting viral RNA, specifically Single-stranded RNA (ssRNA). Consequently, D corresponds to IV.
Correct Matching Summary
The established pairings are:
- A. TLR 3 – II. Double stranded RNA
- B. TLR 4 – I. Lipopolysaccharide
- C. TLR 5 – III. Flagellin
- D. TLR 7 – IV. Single stranded RNA
This complete matching set (A-II, B-I, C-III, D-IV) is represented by the correct option.
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