In humans, which organ converts ammonia (which is toxic) to urea?
Liver
The question asks which human organ is responsible for detoxifying ammonia into urea.
Protein metabolism in cells produces ammonia, which is highly toxic to tissues. In the human liver, the hepatocytes carry out the ornithine cycle (urea cycle), combining ammonia with carbon dioxide to form the much less toxic compound urea, which is then released into the blood and filtered out by the kidneys.
The kidney only excretes the urea produced; the pancreas secretes digestive enzymes and insulin; the large intestine absorbs water. None of these can convert ammonia to urea.
Hence, Liver.
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