Question
Find out correct combination in the following :
A. Import of a protein into an organelle usually occurs in three stages : recognition, translocation and maturation
B. The protein is unfolded for translocation
C. Threading of the protein through membrane does not require energy
D. Targeting sequences on the protein are recognised in the nucleus
Choose the correct answer from the options given below :
This question was previously asked in
CUET PG 2026 Agri-Business Management Question Paper (25-Mar-2026) (Shift 2)
The correct answer is
A and B Only
Key Concepts in Protein Import
This question assesses understanding of the process by which proteins are imported into cellular organelles.
Statement Analysis
- A. Import Stages: Protein import into organelles typically involves three main steps: recognition (of targeting signals), translocation (movement across the membrane), and maturation (folding and modification within the organelle). This statement is correct.
- B. Protein Folding during Translocation: For efficient passage through membrane channels (like TOM or TIM complexes in mitochondria, or the Sec translocon in the ER), proteins usually need to be in an unfolded or partially unfolded state. Chaperones often assist in maintaining this state. This statement is correct.
- C. Energy Requirement for Translocation: Translocation of proteins across organelle membranes is an active process that generally requires energy, often supplied by ATP hydrolysis or GTP hydrolysis, and sometimes electrochemical gradients. This statement is incorrect.
- D. Recognition of Targeting Sequences: Targeting sequences are typically recognized in the cytoplasm by receptor proteins or chaperones associated with the target organelle's membrane, not within the nucleus itself (unless the target is the nucleus, and even then, recognition occurs at the nuclear pore complex). This statement is incorrect.
Conclusion
Based on the analysis, statements A and B are correct. Therefore, the correct combination is A and B Only.
Was this answer helpful?
Similar Questions
- Total score for class IV (upper lower) as per Kuppu Swamy's scale is in one of the following ranges :
- Chancroid is caused by which of the following pathogenic agents ?
- Ehlers - Danlos syndrome illustrates a genetic defect of ?
- Galactosyl transferase is a marker associated with ?
- An infectious agent being present in an inanimate articles the skin surface, particularly on hands, is called :
- The mode followed in transmission of microfilaria through a female culex mosquito is :
- The form(s) available on Integrated Health Information Platform (IHIP) under integrated disease surveillance programme (IDSP) portal to enable data entry is/are :
- Which of the following vaccines, was used first time to immunize humans and included in Expanded Program on Immunization (EPI) :
- The first human disease to be conclusively proved to be caused by a microorganism as well as first disease against which effective vaccine has been developed :
- The mode followed in transmission of plague bacillus in the mouth of a rat flea is :
Important Questions from Miscellaneous
- Which of the following relationships is/are not true?
(A). Most probable velocity = $\sqrt{\frac{2RT}{M}}$
(B). PV = $\frac{3}{2}kT$
(C). Compressibility factor Z = $\frac{pV}{nRT}$
(D). Average kinetic energy of gas = $\frac{1}{2}kT$
Choose the correct answer from the options given below - Match List-I with List-II
List-I List-II Electronic Configuration First Ionisation energy (kJ mol$^{-1}$) (A). ns$^2$ (I). 2100 (B). ns$^2$np$^1$ (II). 1400 (C). ns$^2$np$^3$ (III). 800 (D). ns$^2$np$^6$ (IV). 900
Choose the correct answer from the options given below: - The shielding constant of a 2p electron (calculated using Slater's rules) is
- Match List-I with List-II
List-I List-II Spectroscopy Property (A). Raman (I). Polarizability (B). FTIR (II). Dipole Moment (C). UV-Visible (III). Absorbance (D). NMR (IV). Spin
Choose the correct answer from the options given below: - The structure of protein comprises of:
(A). Primary structure of protein is associated with amino acids
(B). Secondary structure of protein is associated to peptides
(C). Tertiary structure of protein is associated with polypeptide chains
(D). Quaternary structure of protein is associated with polypeptide chains
Choose the correct answer from the options given below:
Need Expert Advice?
Upcoming Exams
GATE
February 06, 2027
Test Series
CUET
CUET PG Psychology (HUQP20) 2026 Mock Test Series
10 Tests
781 Attempts
3.7(15)
English
More Questions from CUET PG
