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Question

As per the National Vector Borne Disease Control Programme, the first-line agent for treatment of Kala-azar (visceral leishmaniasis) is:

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Amphotericin B, liposomal, IV, single dose

Under India's Kala-azar Elimination Programme (NVBDCP), single-dose liposomal Amphotericin B (approximately 5 mg/kg IV) has replaced the older prolonged regimens (sodium stibogluconate, conventional amphotericin B deoxycholate) as the first-line therapy due to its high efficacy, safety, and short duration.

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