A patient with severe lung disease has reduced oxygen intake. Which cellular pathway is likely to be upregulated in their muscle cells during exertion, and what product accumulates as a result?
Anaerobic conversion of pyruvate to lactic acid, leading to lactic acid accumulation
Reduced oxygen supply forces muscle cells to rely on anaerobic respiration, in which pyruvate is converted to lactic acid instead of being fully oxidised, causing lactic acid to build up and cause fatigue.
Hence, anaerobic conversion of pyruvate to lactic acid, leading to lactic acid accumulation, is correct.
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