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Question

A medicine is known to be 75% effective to cure a patient. If the medicine is given to 5 patients, what is the probability that at least one patient is cured by this medicine?

This question was previously asked in
NDA I 2016 GAT Previous Year Paper (17-Apr-2016)
The correct answer is \(\frac{{1023}}{{1024}}\)

Understanding Probability of Medicine Effectiveness

This problem asks for the probability that at least one patient is cured by a medicine with a known effectiveness rate. We are given the probability of success for a single patient and the total number of patients. This scenario fits the characteristics of a binomial probability distribution.

Identifying the Problem Parameters

In this case, we can define:

  • Success (S): The medicine cures a patient.
  • Failure (F): The medicine does not cure a patient.

The given information is:

  • Probability of success, \(p = 75\% = \frac{75}{100} = 0.75\).
  • Probability of failure, \(q = 1 - p = 1 - 0.75 = 0.25\).
  • Number of trials (patients), \(n = 5\).

We want to find the probability that at least one patient is cured. This means the number of cured patients, let's call it \(X\), is 1 or more (\(X \ge 1\)).

Using the Complement Rule

Calculating the probability of "at least one" success directly involves summing the probabilities for \(X=1, X=2, X=3, X=4,\) and \(X=5\). A simpler approach is to use the complement rule of probability:

\[ P(\text{at least one success}) = 1 - P(\text{no successes}) \] In this problem, "no successes" means that none of the 5 patients are cured. This corresponds to \(X=0\).

Calculating Probability of No Patients Cured

The probability of exactly \(k\) successes in \(n\) trials for a binomial distribution is given by the formula:

\[ P(X=k) = \binom{n}{k} p^k q^{n-k} \] We need to find \(P(X=0)\) with \(n=5\), \(k=0\), \(p=0.75\), and \(q=0.25\):

\[ P(X=0) = \binom{5}{0} (0.75)^0 (0.25)^{5-0} \] Let's break down the components:

  • \(\binom{5}{0}\) is the number of ways to choose 0 successes from 5 trials. \(\binom{n}{k} = \frac{n!}{k!(n-k)!}\), so \(\binom{5}{0} = \frac{5!}{0!(5-0)!} = \frac{5!}{0!5!} = 1\) (since \(0! = 1\)).
  • \((0.75)^0 = 1\) (any non-zero number raised to the power of 0 is 1).
  • \((0.25)^5\). We can write \(0.25\) as \(\frac{1}{4}\). So, \((0.25)^5 = \left(\frac{1}{4}\right)^5 = \frac{1^5}{4^5}\).

Calculating \(4^5\):

  • \(4^1 = 4\)
  • \(4^2 = 4 \times 4 = 16\)
  • \(4^3 = 16 \times 4 = 64\)
  • \(4^4 = 64 \times 4 = 256\)
  • \(4^5 = 256 \times 4 = 1024\)

So, \((0.25)^5 = \frac{1}{1024}\).

Now, substitute these values back into the formula for \(P(X=0)\):

\[ P(X=0) = 1 \times 1 \times \frac{1}{1024} = \frac{1}{1024} \] This is the probability that none of the 5 patients are cured by the medicine.

Calculating Probability of At Least One Patient Cured

Using the complement rule:

\[ P(\text{at least one patient cured}) = 1 - P(\text{none cured}) \] \[ P(X \ge 1) = 1 - P(X=0) \] \[ P(X \ge 1) = 1 - \frac{1}{1024} \] To subtract, find a common denominator:

\[ 1 = \frac{1024}{1024} \] \[ P(X \ge 1) = \frac{1024}{1024} - \frac{1}{1024} = \frac{1024 - 1}{1024} = \frac{1023}{1024} \] The probability that at least one of the 5 patients is cured by the medicine is \(\frac{1023}{1024}\).

Event Probability
Medicine cures a patient (Success, \(p\)) 0.75 or \(\frac{3}{4}\)
Medicine does not cure a patient (Failure, \(q\)) 0.25 or \(\frac{1}{4}\)
Number of patients (\(n\)) 5
Probability of none cured (\(P(X=0)\)) \(\left(\frac{1}{4}\right)^5 = \frac{1}{1024}\)
Probability of at least one cured (\(P(X \ge 1)\)) \(1 - P(X=0) = 1 - \frac{1}{1024} = \frac{1023}{1024}\)

Conclusion on Medicine Effectiveness Probability

The probability that at least one patient is cured when the medicine is given to 5 patients, with a 75% effectiveness rate per patient, is \(\frac{1023}{1024}\).

Revision Table: Probability Concepts

Concept Description Formula Example
Probability of Success (\(p\)) The likelihood of a desired outcome in a single trial. Given as 75% or 0.75
Probability of Failure (\(q\)) The likelihood of the outcome not being a success. \(q = 1 - p\). \(1 - 0.75 = 0.25\)
Binomial Probability Probability of exactly \(k\) successes in \(n\) independent trials. \(P(X=k) = \binom{n}{k} p^k q^{n-k}\)
Complement Rule The probability of an event not happening is 1 minus the probability of the event happening. \(P(A') = 1 - P(A)\)
At Least One Probability Probability of 1 or more successes. Often calculated as \(1 - P(\text{zero successes})\). \(P(X \ge 1) = 1 - P(X=0)\)

Additional Information on Binomial Distribution and Probability

The binomial distribution is used for experiments that have the following characteristics:

  • A fixed number of trials (\(n\)). In this problem, \(n=5\).
  • Each trial is independent. The outcome for one patient does not affect others.
  • There are only two possible outcomes for each trial: success (cured) or failure (not cured).
  • The probability of success (\(p\)) is constant for each trial. In this problem, \(p=0.75\) for every patient.

The complement rule is a very useful tool in probability. It simplifies calculations for events like "at least one" by allowing us to calculate the probability of the opposite event (none) and subtract it from 1. This is particularly helpful when the number of trials is large, as it avoids summing many individual probabilities.

In this specific problem, \(\binom{5}{0}\) represents the number of ways to choose which of the 5 patients are cured if none are cured. There is only 1 way for none to be cured (i.e., all fail), which aligns with \(\binom{5}{0}=1\).

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Important Questions from Binomial Distribution

  1. Indicate the correct answer for the combination from the following regarding the conditions for the applicability of a binominal distribution:

    (a) There are n independent trials

    (b) Each trial has only two possible outcomes

    (c) The probabilities of two outcomes do not remain constant

    (d) The trials are independent

    Which of the following options is correct?

  2. In which of the following practical situations, Poisson Distribution can be used?

    A. Number of customers arriving at the super markets per hour.

    B. Number of typographical errors per page in a typed material.

    C. Number of accidents taking place per day on a busy road.

    D. Dice throwing problems.

    E. Number of defective material say, blades, etc. in a packing manufactured by a good concern.

    Choose the most appropriate answer from the options given below:

  3. For Binomial distribution, n = 10 and p = 0.6, E(X 2) (second moment about origin) is:

  4. The mean and variance of binomial distribution B (x, n, p) are 4 and \(\dfrac{4}{3}\) respectively. What is the probability of getting 2 successes?

  5. Find out the fallacy if any in the statement:

    “The mean and the variance of a binomial distribution is 16.2 and 29.4 respectively.”

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