UPSC CMS 2026 General Medicine and Pediatrics Question Paper (2-Aug-2026)

Question 1

A 35-year-old man presented with serial blood pressure recordings of above 140/90 mmHg. Which one of the following signs is not a clue for an underlying cause of hypertension (secondary hypertension)?

Accepted Answer

Vitiligo

Answer

Radio-femoral delay

Answer

Enlarged kidneys

Answer

Bull neck and buffalo hump

Question 2

A 71-year-old male presents with headache, dizziness, nausea with palpitations. The patient is already on treatment for diabetes and hypertension. The blood pressure reading is 220/140 mmHg. Which of the following statements is/are correct?1. This is a case of hypertensive emergency which can be managed by intravenous sodium nitroprusside.2. An immediate normalization of the blood pressure should be the target.3. Secondary causes of hypertension like renovascular disease are uncommon in patients with hypertensive emergency.Select the answer using the code given below:

Accepted Answer

1 only

Answer

1, 2 and 3

Answer

2 and 3 only

Answer

1 and 3 only

Question 3

Match List I with List II and select the correct answer using the code given below the lists:List I (Drug used in heart failure)List II (Mechanism of action)A. MetoprololB. TelmisartanC. EnalaprilD. Eplerenone1. Aldosterone antagonist2. Angiotensin-receptor blocker3. ACE inhibitor4. Beta-blocker

Accepted Answer

A-4, B-2, C-3, D-1

Answer

A-4, B-3, C-2, D-1

Answer

A-1, B-3, C-2, D-4

Answer

A-1, B-2, C-3, D-4

Question 4

Consider the following statements regarding Takotsubo cardiomyopathy:1. There is acute right ventricular dysfunction characterized by dilatation of the right ventricular apex.2. It can be precipitated by acute emotional stress and is frequently associated with an underlying neuro-psychiatric disorder.3. Symptoms and ECG findings often mimic acute ST-elevation myocardial infarction.4. Ventriculography shows normal left ventricle and apical ballooning of the right ventricle.Which of the statements given above are correct?

Accepted Answer

2 and 3

Answer

1 and 2

Answer

1 and 4

Answer

3 and 4

Question 5

With regard to hypertrophic cardiomyopathy, match List I with List II and select the correct answer using the code given below the lists:List I (Mutation)List II (Phenotype)A. Beta-myosin heavy chain mutationsB. Troponin mutationsC. Myosin-binding protein-C mutations1. Marked ventricular hypertrophy2. Hypertension and arrhythmia3. Myocardial fibre disarray with minimal hypertrophy

Accepted Answer

A-1, B-3, C-2

Answer

A-1, B-2, C-3

Answer

A-3, B-2, C-1

Answer

A-2, B-1, C-3

List I (Drug used in heart failure)	List II (Mechanism of action)
A. Metoprolol B. Telmisartan C. Enalapril D. Eplerenone	1. Aldosterone antagonist 2. Angiotensin-receptor blocker 3. ACE inhibitor 4. Beta-blocker

List I (Mutation)	List II (Phenotype)
A. Beta-myosin heavy chain mutations B. Troponin mutations C. Myosin-binding protein-C mutations	1. Marked ventricular hypertrophy 2. Hypertension and arrhythmia 3. Myocardial fibre disarray with minimal hypertrophy