A chemodectoma is a historical term for a tumour arising from chemoreceptor cells, typically located outside the adrenal medulla. These are now generally classified as paragangliomas.
The key is to identify which option represents a tumour originating from such cells.
Based on the origin from chemoreceptor cells (paraganglia), the carotid body tumour is the correct example of a chemodectoma.
Which of the following are correct regarding Li-Fraumeni syndrome?
1. It has autosomal dominant inheritance and is associated with P53 gene.
2. It has autosomal recessive inheritance and is associated with P53 gene.
3. It is associated with an increased risk of sarcomas and leukaemia.
4. It is associated with an increased risk of brain tumours and osteo- sarcomas.
Select the answer using the code given below.