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Question

Which one of the following is an example of a chemodectoma?

The correct answer is
Carotid body tumour

Chemodectoma Identification

A chemodectoma is a historical term for a tumour arising from chemoreceptor cells, typically located outside the adrenal medulla. These are now generally classified as paragangliomas.

The key is to identify which option represents a tumour originating from such cells.

Tumour Origin Analysis

  • Carotid body tumour: These tumours arise from the carotid body, which contains paraganglion cells (chemoreceptors). Therefore, a carotid body tumour is a classic example of a chemodectoma/paraganglioma.
  • Cock's peculiar tumour: This is another name for keratoacanthoma, a benign or low-grade squamous cell proliferation, not related to chemoreceptors.
  • Cystosarcoma phylloides: This is a rare breast tumour, distinct from neuroendocrine or chemoreceptor-derived tumours.
  • Keratoacanthoma: As mentioned, this is a skin lesion, specifically a rapidly growing papule or nodule, unrelated to chemodectomas.

Based on the origin from chemoreceptor cells (paraganglia), the carotid body tumour is the correct example of a chemodectoma.

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Important Questions from Tumours

  1. Which types of cancer are associated with exposure to ionizing radiation? 

    1. Leukaemia 

    2. Lung cancer 

    3. Breast cancer 

    4. Lymphoma 

    Select the correct answer using the code given below.

  2. Which of the following are correct regarding Li-Fraumeni syndrome? 

    1. It has autosomal dominant inheritance and is associated with P53 gene. 

    2. It has autosomal recessive inheritance and is associated with P53 gene. 

    3. It is associated with an increased risk of sarcomas and leukaemia. 

    4. It is associated with an increased risk of brain tumours and osteo- sarcomas. 

    Select the answer using the code given below.

  3. A 25 year old female patient with previous history of neck irradiation presents with thyroid swelling for last 6 months. The patient is clinically euthyroid. On examination, the right lobe of thyroid gland is enlarged with presence of ipsilateral cervical lymphadenopathy. The most probable clinical diagnosis in this patient is
  4. Which of the following statements regarding Carcinoid tumour are correct? 

    1. Terminal ileum is the most common site for these tumours in the gastrointestinal tract 

    2. These tumors arise from Kulchitsky cells situated at the base of intestinal crypts 

    3. 5-Hydroxytryptamine is the most common vasoactive peptide produced by these tumors 

    4. Serum chromogranin A is a useful marker for disease recurrence 

    Select the correct answer using the code given below :

  5. Which one of the following is correct regarding Gastrointestinal Stromal Tumour (GIST)?
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