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Question

Which one of the following is an example of a chemodectoma?

The correct answer is
Carotid body tumour

Chemodectoma Identification

A chemodectoma is a historical term for a tumour arising from chemoreceptor cells, typically located outside the adrenal medulla. These are now generally classified as paragangliomas.

The key is to identify which option represents a tumour originating from such cells.

Tumour Origin Analysis

  • Carotid body tumour: These tumours arise from the carotid body, which contains paraganglion cells (chemoreceptors). Therefore, a carotid body tumour is a classic example of a chemodectoma/paraganglioma.
  • Cock's peculiar tumour: This is another name for keratoacanthoma, a benign or low-grade squamous cell proliferation, not related to chemoreceptors.
  • Cystosarcoma phylloides: This is a rare breast tumour, distinct from neuroendocrine or chemoreceptor-derived tumours.
  • Keratoacanthoma: As mentioned, this is a skin lesion, specifically a rapidly growing papule or nodule, unrelated to chemodectomas.

Based on the origin from chemoreceptor cells (paraganglia), the carotid body tumour is the correct example of a chemodectoma.

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Important Questions from Tumours

  1. Which one of the following is NOT correct regarding MEN-1 syndrome?
  2. All of the following are hormonal agents used in treatment of cancer EXCEPT:
  3. Which one of the following is NOT associated with BRCA1/BRCA2 genes ?
  4. Which of the following are correct regarding Li-Fraumeni syndrome? 

    1. It has autosomal dominant inheritance and is associated with P53 gene. 

    2. It has autosomal recessive inheritance and is associated with P53 gene. 

    3. It is associated with an increased risk of sarcomas and leukaemia. 

    4. It is associated with an increased risk of brain tumours and osteo- sarcomas. 

    Select the answer using the code given below.

  5. Which one of the following is correct regarding Gastrointestinal Stromal Tumour (GIST)?
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