Hormonal Agents in Cancer Therapy Identification
This question asks to identify the agent that is NOT a hormonal therapy used in cancer treatment from the given options.
Understanding Hormonal Cancer Agents
Hormonal agents work by targeting hormones that fuel certain types of cancer growth, like breast or prostate cancer. They either lower the amount of hormone the body makes or block hormones from acting on cancer cells.
Analysis of Options
- Anastrazole: This is an aromatase inhibitor. It lowers estrogen levels and is used to treat hormone-sensitive breast cancer in postmenopausal women. It is a hormonal agent.
- Irinotecan: This drug is a type of chemotherapy, specifically a topoisomerase inhibitor. It works by interfering with DNA replication in rapidly dividing cancer cells. It is NOT a hormonal agent.
- Cabergoline: While primarily used for conditions like hyperprolactinemia, its mechanism involves dopamine receptors, which interact with hormonal systems. In some contexts related to endocrine tumors or hormonal influences on cancer, it can be considered relevant to hormonal therapy.
- Leuprolide: This is a gonadotropin-releasing hormone (GnRH) agonist. It suppresses the production of sex hormones (testosterone and estrogen) and is used in treating hormone-sensitive cancers like prostate and breast cancer. It is a hormonal agent.
Conclusion
Based on the analysis, Irinotecan is a chemotherapy drug, not a hormonal agent. The other listed drugs function as hormonal agents or modulate hormonal pathways relevant to cancer treatment.
Important Questions from Tumours
Which types of cancer are associated with exposure to ionizing radiation?
1. Leukaemia
2. Lung cancer
3. Breast cancer
4. Lymphoma
Select the correct answer using the code given below.
Which of the following are correct regarding Li-Fraumeni syndrome?
1. It has autosomal dominant inheritance and is associated with P53 gene.
2. It has autosomal recessive inheritance and is associated with P53 gene.
3. It is associated with an increased risk of sarcomas and leukaemia.
4. It is associated with an increased risk of brain tumours and osteo- sarcomas.
Select the answer using the code given below.
- A 25 year old female patient with previous history of neck irradiation presents with thyroid swelling for last 6 months. The patient is clinically euthyroid. On examination, the right lobe of thyroid gland is enlarged with presence of ipsilateral cervical lymphadenopathy. The most probable clinical diagnosis in this patient is
Which of the following statements regarding Carcinoid tumour are correct?
1. Terminal ileum is the most common site for these tumours in the gastrointestinal tract
2. These tumors arise from Kulchitsky cells situated at the base of intestinal crypts
3. 5-Hydroxytryptamine is the most common vasoactive peptide produced by these tumors
4. Serum chromogranin A is a useful marker for disease recurrence
Select the correct answer using the code given below :
- Which one of the following is correct regarding Gastrointestinal Stromal Tumour (GIST)?
