Which of the following statements regarding human antibodies is/are accurate? 1. IgG constitutes the largest proportion of antibodies in human blood. 2. IgE plays a key role in allergic responses. 3. IgA is primarily located in bodily secretions such as saliva and breast milk.
1, 2 and 3 all are correct
Statement 1 ✓ — IgG is the most abundant antibody in human serum, constituting about 75–80% of total serum immunoglobulins.
Statement 2 ✓ — IgE binds to mast cells and basophils and triggers allergic responses (e.g., hay fever, asthma) upon antigen exposure.
Statement 3 ✓ — Secretory IgA (sIgA) is the predominant antibody in mucosal secretions including saliva, tears, intestinal fluid, and breast milk.
All three statements are correct. Hence Option D is correct.
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