This question asks to identify the specific form of thyroid hormone that functions as the active agent in stimulating metabolism via gene expression, acting through a nuclear receptor. Key characteristics include being an active form, utilizing a nuclear receptor, and enhancing energy-yielding metabolism through increased expression of catabolic enzyme genes.
Thyroid Hormone Action Explained
Thyroid hormones are crucial for regulating metabolism. They exert their effects primarily by binding to specific nuclear receptors, which then interact with DNA to modify the expression of target genes. This process influences various metabolic functions, including energy production and breakdown of substrates.
Thyroxine (T4) Role
Thyroxine, also known as T4, is one of the two major hormones produced by the thyroid gland. While T3 (Triiodothyroxine) is often considered the more potent form, T4 also plays a significant role. T4 circulates in the blood and can act directly or be converted peripherally into T3. It binds to thyroid hormone receptors, which are nuclear receptors.
- T4 interacts with nuclear receptors.
- This interaction influences gene expression.
- It stimulates metabolic processes, including increasing the expression of genes for enzymes involved in catabolism (breakdown of molecules for energy).
Therefore, considering the options and the described mechanism, Thyroxine (T4) fits the description as a thyroid hormone acting through a nuclear receptor to stimulate metabolism via gene expression.
Evaluating Other Options
- Thyroglobulin (Tyr) and Thyroglobulin (Tyr-I): These are precursor proteins involved in the synthesis of thyroid hormones, not the active hormones themselves.
- Triiodothyroxine (T3): While T3 is highly active, the provided correct answer points to T4. T4 functions in the described pathway, often serving as a reservoir or prohormone converted to T3, but its interaction with nuclear receptors and influence on metabolism is significant.
Based on the provided correct answer being Thyroxine (T4), it is identified as the hormone fulfilling the described functions.
Similar Questions
Which of the following is an active form of thyroid hormone that acts through a nuclear receptor to stimulate energy-yielding metabolism by increasing the expression of genes encoding key catabolic enzymes ?
- Primary changes in Acid Base disorders are :
A. Metabolic acidosis decreased plasma bicarbonate
B. Metabolic alkaloses decreased plasma bicarbonate
C. Respiratory alkalosis decreased $pco_{2}$
D. Respiratory acidosis decreased $pco_{2}$
Choose the correct answer from the options given below : - Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : A covlent single bonds in biological molecules have energies similar to the energy of the C-C bond in ethane.
Reason (R) : It is because less electrons are shared between atoms in double bonds they require more energy to break than single bonds.
In the light of the above statements, choose the most appropriate answer from the options given below : - A solution is called hypertonic when :
List - I shows various isotopes and List - II indicates their half-lives.
Match List - I with List - II.
List - I List - II A. ${ }^{3}\text{H}$ I. 60 days B. ${ }^{14}\text{C}$ II. 14.5 days C. ${ }^{32}\text{P}$ III. 5700 years D. ${ }^{125}\text{I}$ IV. 12.2 years
Choose the correct answer from the options given below :- Based on the position of Centromere Chromosome can be divided into 4 types :
A. Meta centric : Centromere in the middle
B. Submetacentric : Centromere at the end
C. Telocentric : Terminal Centromere
D. Acrocentric : Centromere is close to middle
Choose the correct answer from the options given below : - Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : Neurons are the functional cells in brain. Glial cells are the supporting cells of the brain.
Reason (R) : Astroglia are starshaped neuronal cells.
In the light of the above statements, choose the most appropriate answer from the options given below : - Which of the following are the correct components of PCR reation ?
A. Taq Polymerase
B. Buffer (5X)
C. Primers (F and R)
D. NTPs
E. $\\text{H}_{2}\\text{O}$
Choose the correct answer from the options given below : - List the proteins detection techniques in increasing order of sensitivity :
A. Bradford
B. Biuret
C. Lowry
Choose the correct answer from the options given below : - Match List - I with List - II.
List - I List - II A. ELISA I. Visualization of cells B. RIA II. Proteins identification C. Centrifugation III. Hormone detection D. Microscopy IV. Isolation of organelles
Choose the correct answer from the options given below :
Important Questions from Mixed Topic (CUET PG)
- Who was the founder of Bolshevik Communist party?
- What is the key guide to statecraft in the realist tradition?
- Chronologically arrange the events in the Cold War period.
A. Berlin Wall is constructed
B. Communist China joins the UN
C. Soviet invasion of Czechoslovakia
D. Berlin Blockade
Choose the correct answer from the options given below: Morgenthau's principles of political realism are:
A. Politics is rooted in permanent and unchanging human nature which is basically self centred, self-regarding and self-interested
B. Politics is an autonomous sphere of action and cannot therefore be reduced to morals
C. International Politics is an arena of conflicting self-interests
D. The ethics of international relations is situational ethics which is very different from private morality
Choose the correct answer from the options given below:Who among the following political thinkers consider the anarchical self help system to be a compelling factor for States to maximise their relative power positions?
