Allele Frequency Definition
Allele frequency represents how common an allele is within a population. It is calculated as the number of copies of a specific allele divided by the total number of copies of all alleles for that gene in the population.
Population Parameters
In this haploid population:
- Total number of individuals = N
- Since the population is haploid, the total number of alleles at the locus = N
- Number of copies of allele AL1 = Z1
- Number of copies of allele AL2 = Z2
Calculating AL2 Allele Frequency
The frequency of allele AL2 is determined using the following formula:
Frequency of AL2 = (Number of copies of AL2) / (Total number of alleles)$
Substituting the given values:
Frequency of AL2 = $ \frac{Z2}{N} $
Therefore, the frequency of allele AL2 in the population is $ \frac{Z2}{N} $.
Important Questions from Allele frequencies
- Consider a diploid population at Hardy-Weinberg equilibrium. For a locus with two alleles, the frequency of the $A_1A_1$ genotype is 0.01. The frequency of heterozygotes $A_1A_2$ is ________ (answer up to 2 decimal places).
- The frequency of an allele at a locus on the non-recombining region of the Y chromosome in humans is 0.3. If the population size is N and the sex ratio is 1:1, what is the number of copies of the alleles in the population?
The graph shows the relationship between a variable on the x-axis and genetic diversity on the y-axis. Each point represents a species and the trend line describes the relationship across species.
Select the most appropriate variable for the x-axis.- In a population, the frequency of an allele changes with time as given in the table:Which one of the following describes how allele frequency changes with year?
Year (x) 0 10 20 30 40 Allele frequency (y) 0.1 0.2 0.3 0.4 0.5
