5'-TTAGGG-3'
Understanding Telomere Repeat Sequence
Telomeres are protective caps at the ends of chromosomes.
They consist of repetitive nucleotide sequences.
In humans and many other vertebrates, the specific repeat sequence found at the telomeres is essential for maintaining chromosome integrity during cell division.
Identifying the Human Telomere Sequence
The standard repeat sequence for human telomeres is:
- 5'-TTAGGG-3'
This sequence is repeated thousands of times.
Let's examine the options provided:
- Option 1: $5'-TATAAT-3'$ is a promoter sequence element (TATA box).
- Option 2: $5'-TTAGGG-3'$ matches the known human telomere repeat sequence.
- Option 3: $5'-GGGCCC-3'$ is not the standard human telomere repeat.
- Option 4: $5'-AAAAAA-3'$ is not the standard human telomere repeat.
Therefore, the correct repeat sequence of telomere in humans is $5'-TTAGGG-3'$.
Important Questions from Molecular Structure of Genes and Chromosomes
Consider the following multiple sequence alignment of four DNA sequences.
$\begin{matrix}A & C & T & A \\ A & C & T & G \\ A & G & T & C \\ A & G & C & T \end{matrix} $
Shannon's entropy of the above alignment is ________.
- All pseudogenes DO NOT code for a __________.
- C-value paradox refers to
The transcription factor X binds a 10 base pair DNA stretch. In the DNA of an organism, X was found to bind at 20 distinct sites. An analysis of these 20 binding sites showed the following distribution:
Base Position in the binding site 1 2 3 4 5 6 7 8 9 10 A 11 0 0 0 16 2 4 0 4 3 T 3 0 19 0 1 3 4 20 2 4 G 4 20 0 0 2 4 6 0 12 2 C 2 0 1 20 1 11 6 0 2 11 What is the consensus sequence for the binding site of X?
- Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?
P. A larger E-value indicates higher sequence similarity
Q. E-value < $10^{-10}$ indicates sequence homology
R. A higher BLAST score indicates higher sequence similarity
S. E-value > $10^{10}$ indicates sequence homology
