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Question

Read Assertion (A) and Reason (R) carefully and select the option :

Assertion (A) : In glycolysis, 4 ATPs are produced.

Reason (R) : The net gain of ATP in glycolysis is 8 ATP.

This question was previously asked in
MH SET 2026 Paper 1 Question Paper (25-Oct-2026)
The correct answer is

(A) is false, but (R) is true

In glycolysis glucose is split into 2 pyruvate; 4 ATP are formed directly by substrate-level phosphorylation and 2 NADH are produced, while 2 ATP are used up in the early steps.

In the classical accounting for aerobic conditions each NADH yields 3 ATP through the electron transport chain, so total ATP produced in glycolysis is 4 + 6 = 10, and the net gain after deducting the 2 ATP used is 8 ATP.

So, on this accounting, the claim that only 4 ATP are produced understates the total yield and is taken as false, while the statement that the net gain is 8 ATP is true.

Therefore the Assertion is false and the Reason is true, so the Reason cannot explain the Assertion.

Hence, (A) is false, but (R) is true.

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