LIST-I
Anti cancer agentLIST-II
StagesA. Etoposide I. G1 B. Hydroxyurea II. S C. Topotecan III. M D. Paclitaxel IV. G2
Choose the correct answer from the options given below:
To solve this question, we need to match each anticancer agent from List I with the correct stage of cell cycle inhibition from List II. Let's examine each agent:
- Etoposide: Etoposide is a chemotherapeutic agent that inhibits the enzyme topoisomerase II, leading to breaks in DNA and thereby hampering cell division. It primarily acts in the G2 phase of the cell cycle. Therefore, Etoposide aligns with I. G2.
- Hydroxyurea: Hydroxyurea inhibits ribonucleotide reductase, leading to decreased DNA synthesis. This agent is known to halt the cell cycle in the S phase, where DNA replication occurs. So, Hydroxyurea aligns with II. S.
- Topotecan: Topotecan is another topoisomerase inhibitor, primarily acting on topoisomerase I. Although it affects the cell cycle during DNA replication, its major effect is seen at the S phase. Thus, Topotecan should be aligned with III. S.
- Paclitaxel: Paclitaxel (also known as Taxol) disrupts microtubule functions, preventing cell division by arresting the cells in the mitotic phase. It acts specifically in the M phase. Therefore, Paclitaxel corresponds to IV. M.
Given the above analysis, the correct match is:
- A - IV (Etoposide matches with G2)
- B - II (Hydroxyurea matches with S)
- C - III (Topotecan matches with S)
- D - I (Paclitaxel matches with M)
Therefore, the correct option is A-II, B-II, C-III, D-I.
Similar Questions
- Correct sequence of chemical entities involved in nucleic acid synthesis in bacteria is:
A. Para amino benzoic acid
B. Tetrahydro folate
C. Dihydrofolate
D. DNA
Choose the correct answer from the options given below: - G Protein receptor activation follows the sequence:
A. Activation of protein kinase A
B. ATP to Cyclic AMP
C. Release of calcium ion
D. Muscle contraction
Choose the correct answer from the options given below: - Oral absorption of drugs in neonate compared to older children and adults
A. Phenytoin: Decreased
B. Digoxin : Decreased
C. Phenobarbital : Increased
D. Ampicillin: Increased
Choose the correct answer from the options given below: - The possible toxicities of antibiotics :
A. Polymyxin B: Anabolic effect
B. Chloroamphnicol: Bone marrow depression
C. Aminoglycosides : 8th cranial nerve toxicity
D. Vancomycin: Hearing loss
Choose the correct answer from the options given below: - Pyrrolidine alkaloid is present in:
- Which of the phytoconstituent is confirmed by Baljet test (Sodium picrate solution)?
- Cassia bark contains all except:
- Correct sequence of biogenetic pathway reactions in Shikimic acid biosynthesis from Phosphoenolpyruvic acid and erythrose 4-phosphate is:
A. 2-keto-3-deoxy-7-phospho-D-glucoheptonic acid
B. 3-dehydroshikimic acid
C. Shikimic acid
D. 3-dehydroquinic acid
Choose the correct answer from the options given below: - Match List I with List II Choose the correct combination of Crude drug and active constituent
LIST-I
Crude drugLIST-II
Active constituentA. Sandalwood I. Apiole B. Rosemerry II. Carvone C. Dill III. Borneol D. Parsley IV. Santalols
Choose the correct answer from the options given below: - Choose the correct expression for ion velocity in mass spectrometry:
Important Questions from Mixed Topic (CUET PG)
- Who was the founder of Bolshevik Communist party?
- What is the key guide to statecraft in the realist tradition?
- Chronologically arrange the events in the Cold War period.
A. Berlin Wall is constructed
B. Communist China joins the UN
C. Soviet invasion of Czechoslovakia
D. Berlin Blockade
Choose the correct answer from the options given below: Morgenthau's principles of political realism are:
A. Politics is rooted in permanent and unchanging human nature which is basically self centred, self-regarding and self-interested
B. Politics is an autonomous sphere of action and cannot therefore be reduced to morals
C. International Politics is an arena of conflicting self-interests
D. The ethics of international relations is situational ethics which is very different from private morality
Choose the correct answer from the options given below:Who among the following political thinkers consider the anarchical self help system to be a compelling factor for States to maximise their relative power positions?
