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Question

How many 3-tuples are possible for the following amino acid sequence? 
MADCMWDISEASE

The correct answer is
11

Counting Consecutive 3-Tuples in Amino Acid Sequence

A 3-tuple, in this context, refers to a consecutive subsequence of three amino acids within the given sequence.

The provided amino acid sequence is: MADCMWDISEASE

First, determine the total number of amino acids in the sequence. Counting each letter:

  • M, A, D, C, M, W, D, I, S, E, A, S, E
  • There are 13 amino acids in the sequence. Let this length be $N = 13$.

To find the number of possible 3-tuples, we can list them starting from each possible position:

  1. MAD
  2. ADC
  3. DCM
  4. CMW
  5. MWD
  6. WDI
  7. DIS
  8. ISE
  9. SEA
  10. EAS
  11. ASE

Counting these listed 3-tuples, we find there are 11 possible combinations.

Alternatively, the number of k-length subsequences (tuples) in a sequence of length $N$ is given by the formula: $N - k + 1$.

In this case, $N = 13$ and $k = 3$.

Number of 3-tuples = $13 - 3 + 1 = 11$.

Therefore, there are 11 possible 3-tuples.

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Important Questions from Molecular Structure of Genes and Chromosomes

  1. All pseudogenes DO NOT code for a __________.
  2. C-value paradox refers to
  3. DNA sample collected from an unidentified bacterial species (Y) contains 13% of adenine. The G+C content (in percentage) of Y is ________
  4. The contour length of a B-DNA molecule that encodes a bacterial protein of 33 kDa is _________ nm. 

    Consider the average molecular weight of an amino acid as 110 Da and helix rise per base pair for B-DNA as 0.34 nm. 

    (Round off to the nearest integer)

  5. Which of the following methods is/are used for identifying histone modifications?
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