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Question

Following the immunotherapy, in patients undergoing renal transplantation, the skin cancer most commonly seen is

The correct answer is
Skin tumors

Renal Transplant Skin Cancer Post-Immunotherapy

Patients undergoing renal transplantation typically require immunosuppressive therapy, often referred to as immunotherapy, to prevent organ rejection. This therapy suppresses the immune system, increasing the risk of various complications, including malignancies.

Among the various risks associated with long-term immunosuppression post-renal transplant, skin cancers become notably more common. The question asks for the most commonly seen skin cancer type.

Common Post-Transplant Skin Cancers

  • Immunosuppression impairs the immune system's ability to detect and eliminate abnormal or cancerous cells, including those originating in the skin.
  • Factors like viral infections (e.g., Human Papillomavirus - HPV) and chronic sun exposure (UV radiation) are more likely to lead to skin cancer development in this vulnerable population.
  • While specific skin cancers like Kaposi's sarcoma or Mycosis Fungoides can occur, the overall category of Skin tumors, particularly non-melanoma skin cancers (like basal cell carcinoma and squamous cell carcinoma), represents the most frequent neoplastic complication affecting the skin.

Therefore, the general classification of Skin tumors is the most accurate answer for the most commonly seen skin cancer in renal transplant patients following immunotherapy.

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Important Questions from Tumours

  1. Which one of the following is NOT correct regarding MEN-1 syndrome?
  2. All of the following are hormonal agents used in treatment of cancer EXCEPT:
  3. Which one of the following is NOT associated with BRCA1/BRCA2 genes ?
  4. Which of the following are correct regarding Li-Fraumeni syndrome? 

    1. It has autosomal dominant inheritance and is associated with P53 gene. 

    2. It has autosomal recessive inheritance and is associated with P53 gene. 

    3. It is associated with an increased risk of sarcomas and leukaemia. 

    4. It is associated with an increased risk of brain tumours and osteo- sarcomas. 

    Select the answer using the code given below.

  5. Which one of the following is correct regarding Gastrointestinal Stromal Tumour (GIST)?
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