Consider the following pancreatic hormones : 1. Insulin 2. Islet amyloid polypeptide or amylin 3. Glucagon 4. Somatostatin Which of the above is/are secreted by beta cells of the pancreatic islets?
Pancreatic Hormone Secretion by Beta Cells
The question asks to identify which pancreatic hormones are secreted by the beta cells ($\beta$ cells) of the pancreatic islets. Let's analyze the secretion sites for each listed hormone:
- 1. Insulin: Secreted by beta cells ($\beta$ cells) in the pancreatic islets.
- 2. Islet amyloid polypeptide (amylin): Also co-secreted by beta cells ($\beta$ cells) along with insulin.
- 3. Glucagon: Secreted by alpha cells ($\alpha$ cells) in the pancreatic islets.
- 4. Somatostatin: Secreted by delta cells ($\delta$ cells) in the pancreatic islets.
Identifying Beta Cell Secretions
Based on the secretion sites:
- Hormones secreted by beta cells ($\beta$ cells) are Insulin (1) and Islet amyloid polypeptide or amylin (2).
- Glucagon (3) is secreted by alpha cells ($\alpha$ cells).
- Somatostatin (4) is secreted by delta cells ($\delta$ cells).
Therefore, the hormones secreted by beta cells of the pancreatic islets are Insulin and Islet amyloid polypeptide (amylin).
This corresponds to options 1 and 2.
Important Questions from Diabetes Mellitus
- A 52-year-old male diabetic presents with recurrent episodes of hypoglycemia. On examination, Pulse : 84 beats/minute, BP : 160/100 mm Hg, Chest and CVS examination unremarkable. Which of the following antihypertensive should be avoided in this patient ?
- Which of the following glucose lowering agent can be given as an injectable drug?
Which of the following findings are seen in Diabetic Retinopathy on fundus examination?
1. Microaneurysm
2. Dot and blot hemorrhage
3. Retinal thickening
4. Neovascularization
Select the correct answer using the code given below:
Which of the following statements are correct with regard to glucose homeostasis?
1. Insulin level rises postprandially.
2. Major portion of postprandial glucose is used by skeletal muscle.
3. Brain uses glucose in an insulin-dependent manner.
4. Glucagon is secreted during exercise.
Select the answer using the code given below :
- Which one of the following insulin preparations has the longest effective duration of action?
