With regard to transfusion therapy, cryoprecipitate is a rich source of which of the following? 1. Fibrinogen 2. Clotting factor VIII 3. Clotting factor IX 4. von Willebrand factor Select the correct answer using the code given below.
Cryoprecipitate Composition
Cryoprecipitate is a blood product derived from plasma. It is specifically prepared to concentrate certain proteins that precipitate when plasma is frozen and thawed. It is primarily used in transfusion therapy to treat specific coagulation deficiencies.
Key Components of Cryoprecipitate
Cryoprecipitate is known to be a rich source of:
- Fibrinogen (Factor I): Essential for clot formation.
- Clotting Factor VIII: Crucial for the intrinsic pathway of coagulation.
- von Willebrand factor (vWF): Important for platelet adhesion and stabilizing Factor VIII.
Clotting Factor IX is typically found in plasma but is not concentrated in cryoprecipitate; it's more concentrated in Prothrombin Complex Concentrates (PCCs).
Identifying the Correct Option
Based on the components concentrated in cryoprecipitate, the correct combination includes Fibrinogen (1), Clotting Factor VIII (2), and von Willebrand factor (4).
Therefore, the correct option is the one that lists 1, 2, and 4.
Important Questions from Coagulation Disorders
- Which of the following is an oral anticoagulant?
- Which one of the following statements is characteristic of Purpura fulminans ?
- Which one of the following correctly describes the mode of inheritance of haemophilia B?
- Which one of the following is correct regarding blood components in clinical practice ?
- Which one of the following drugs causes direct X-a inhibition ?
