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Question

Which of the following is an oral anticoagulant?

The correct answer is
Dabigatran

Identifying Oral Anticoagulants

Anticoagulants are medications that prevent blood clot formation. They can be administered through different routes, primarily orally (by mouth) or parenterally (injection or infusion).

Analyzing Anticoagulant Options

The question asks to identify which of the listed drugs is an oral anticoagulant. Let's examine each option:

  • Dabigatran: This medication is a direct thrombin inhibitor and is taken orally. It is prescribed to prevent stroke and systemic embolism in patients with non-valvular atrial fibrillation and to treat deep vein thrombosis (DVT) and pulmonary embolism (PE).
  • Heparin: This is a widely used anticoagulant, but it is administered parenterally, typically via subcutaneous injection or intravenous infusion. It is not taken orally.
  • Fondaparinux: This is a synthetic indirect factor Xa inhibitor. It is administered via subcutaneous injection and is therefore a parenteral anticoagulant.
  • Bivalirudin: This is another direct thrombin inhibitor, structurally related to hirudin. It is administered intravenously and used primarily during percutaneous coronary interventions. It is a parenteral anticoagulant.

Conclusion on Oral Anticoagulant

Based on the routes of administration:

  • Dabigatran is administered orally.
  • Heparin, Fondaparinux, and Bivalirudin are administered parenterally (injection or infusion).

Therefore, Dabigatran is the correct answer as it is the only oral anticoagulant among the choices.

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Important Questions from Coagulation Disorders

  1. Which one of the following statements is characteristic of Purpura fulminans ?
  2. With regard to transfusion therapy, cryoprecipitate is a rich source of which of the following? 

    1. Fibrinogen 

    2. Clotting factor VIII 

    3. Clotting factor IX 

    4. von Willebrand factor 

    Select the correct answer using the code given below.

  3. Which one of the following correctly describes the mode of inheritance of haemophilia B?
  4. Which one of the following is correct regarding blood components in clinical practice ?
  5. Which one of the following drugs causes direct X-a inhibition ?
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