Question
Which one of the following is a database of protein sequence motifs?
The correct answer is
PROSITE
Understanding Protein Sequence Motif Databases
The question asks to identify the database specifically designed for storing protein sequence motifs. Motifs are short, conserved patterns in protein sequences that are often associated with specific functions or structures.
Database Analysis
- PROSITE: This database is a curated collection of protein families and domains represented by patterns and profiles. It is explicitly designed to store and search for sequence patterns (motifs) that characterize these protein groups.
- TrEMBL: This is a component of the UniProt Knowledgebase (UniProtKB) that contains a large collection of protein sequences that are not yet fully reviewed. While it holds sequences, it's not primarily a motif database.
- SWISSPROT: Also part of UniProtKB, SWISSPROT contains high-quality, manually annotated protein sequences. It focuses on detailed functional information but isn't specifically a motif pattern database like PROSITE.
- PDB: The Protein Data Bank (PDB) is a repository for the 3D structural data of proteins and nucleic acids. It focuses on structure, not sequence motifs.
Conclusion
Based on the analysis, PROSITE is the specialized database for protein sequence motifs.
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Important Questions from Structure and Function of Biomolecules
- Match the carbohydrates in Column I with the correct glycosidic linkages involved in Column II.
Column I Column II P. Amylose 1. $\beta$ ($1\to 4$) Q. Sucrose 2. $\alpha$ ($1\to 4$) R. Amylopectin 3. $\alpha 1\to \beta 2$ S. Cellulose 4. $\alpha$ ($1\to 4$), $\alpha$ ($1\to 6$) - Match the biomolecules in Column I with their function given in Column II
Column I Column II P. Lectins 1. Acts as ATP dependent pump to efflux out small molecules Q. P-glycoprotein 2. Targets lysosomal enzymes to their destination R. Digitoxigenin 3. Specific carbohydrate binding proteins S. Mannose 6-phosphate 4. Inhibits Na$^+$-K$^+$ pump - Which one of the following coenzymes is utilised by alanine racemase for the conversion of L-Alanine to D-Alanine?
- Correctly match the following Monosaccharides with their respective Epimers.
Monosaccharide Epimer P. D-mannose 1. C-3 epimer of D-glucose Q. D-allose 2. C-4 epimer of D-glucose R. D-galactose 3. C-4 epimer of D-mannose S. D-talose 4. C-2 epimer of D-glucose 5. C-5 epimer of D-glucose - Which of the following show(s) optical activity at 100 mM concentration in water?
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