Column I Column II P. Lectins 1. Acts as ATP dependent pump to efflux out small molecules Q. P-glycoprotein 2. Targets lysosomal enzymes to their destination R. Digitoxigenin 3. Specific carbohydrate binding proteins S. Mannose 6-phosphate 4. Inhibits Na$^+$-K$^+$ pump
Biomolecule Function Matching
This section details the matching of key biomolecules with their specific biological functions, essential for understanding cellular mechanisms.
Biomolecule Function Identification
We determine the correct function for each biomolecule by considering its known biological role:
- P. Lectins: These are proteins characterized by their specific binding to carbohydrate structures. Thus, they align with function 3. Specific carbohydrate binding proteins.
- Q. P-glycoprotein: This protein functions as an ATP-driven pump that actively transports small molecules out of cells. It corresponds to function 1. Acts as ATP dependent pump to efflux out small molecules.
- R. Digitoxigenin: A component related to cardiac glycosides, it inhibits the activity of the primary ion transporter in cell membranes. This matches function 4. Inhibits Na$^+$-K$^+$ pump.
- S. Mannose 6-phosphate: This specific modification serves as a targeting signal, directing proteins, particularly lysosomal enzymes, to their correct cellular location. It matches function 2. Targets lysosomal enzymes to their destination.
Summary of Biomolecule Pairings
The accurate pairings derived from the analysis are presented below:
| Column I Item | Column II Function |
| P. Lectins | 3. Specific carbohydrate binding proteins |
| Q. P-glycoprotein | 1. Acts as ATP dependent pump to efflux out small molecules |
| R. Digitoxigenin | 4. Inhibits Na$^+$-K$^+$ pump |
| S. Mannose 6-phosphate | 2. Targets lysosomal enzymes to their destination |
The correct set of matches is P-3, Q-1, R-4, S-2.
Important Questions from Structure and Function of Biomolecules
- An element that is present in a nucleotide but not in a nucleoside is __________.
- Which one of the following coenzymes is utilised by alanine racemase for the conversion of L-Alanine to D-Alanine?
- Which of the following show(s) optical activity at 100 mM concentration in water?
An octapeptide composed of these L-amino acids – Lys, Thr, Ser, Met, Arg, Trp, Tyr, Glu was subjected to analyses with the following outcomes:
P. The N-terminal sequencing analysis by Sanger's method yielded 'Ser' at the N-terminus
Q. Chymotrypsin treatment gave a pentapeptide, a ‘Tyr' containing dipeptide and a free ‘Glu'
R. Cyanogen bromide treatment gave two tetrapeptides
S. Trypsin treatment gave two tripeptides and a dipeptide
Which one of the following is the correct octapeptide sequence?
- Which of the following amino acids contain(s) two chiral carbons?
