Which of the following treatments for a pregnant lady who has been exposed to a patient of chicken pox are correct? 1. Varicella-zoster immune globulin 2. Varicella-zoster vaccine 3. Acyclovir 4. Prednisolone Select the correct answer using the code given below.
Treatment Options for Pregnant Lady Chickenpox Exposure
When a pregnant lady is exposed to chickenpox (caused by the Varicella-Zoster Virus - VZV), the primary concerns are preventing infection in the mother and protecting the fetus. Management strategies focus on prophylaxis and treatment.
Evaluating Treatment Interventions
- 1. Varicella-zoster immune globulin (VZIG): VZIG is recommended for susceptible pregnant women after VZV exposure. It provides passive immunity and can prevent or significantly reduce the severity of chickenpox.
- 2. Varicella-zoster vaccine: This is a live attenuated vaccine. Live vaccines are generally contraindicated during pregnancy due to potential risks to the fetus. It is used for prevention before exposure, not post-exposure management in pregnant women.
- 3. Acyclovir: This antiviral medication is used for the treatment of chickenpox in pregnant women, particularly if the infection develops. It helps manage symptoms and reduce potential complications. In certain high-risk scenarios post-exposure, it might also be considered.
- 4. Prednisolone: Corticosteroids like Prednisolone are typically not indicated for routine management following VZV exposure. Their use can potentially worsen VZV infections and is generally avoided unless specific complications arise.
Identifying Correct Treatments
Based on the evaluation:
- VZIG (1) is a correct post-exposure prophylaxis option for non-immune pregnant women.
- Acyclovir (3) is a correct treatment option if the infection occurs or in specific prophylaxis situations.
Therefore, the correct treatments are Varicella-zoster immune globulin and Acyclovir.
Important Questions from Viral Infections
- A 'slapped cheek' rash is characteristically seen in which of the following infections?
HIV-associated neurocognitive disorder (HAND) includes which of the following?
1. Asymptomatic neurocognitive disorder
2. Minor neurocognitive disorder
3. HIV-associated dementia
Select the correct answer using the code given below.
Which of the following statements are correct regarding Kyasanur forest disease?
1. It is commonly seen in North-Eastern States of India.
2. Monkeys act as reservoir of the disease.
3. Transmission happens through tick bite.
4. Inactivated vaccine is available for its prevention.
Select the correct answer using the code given below.
- Which one of the following has the highest risk of human immunodeficiency virus (HIV) transmission after single exposure to an HIV-infected source ?
- Fever with splenomegaly and lymphadenopathy can be seen in
