Which of the following statements are correct regarding renal cell carcinoma? 1. It arises from the epithelium of the proximal convoluted tubule. 2. It has a female preponderance. 3. Major subtypes are clear cell, papillary and chromophobe. 4. Surgery is the mainstay of treatment for disease. organ-confined Select the answer using the code given below.
Renal Cell Carcinoma Statements Analysis
This solution analyzes the correctness of four statements regarding renal cell carcinoma (RCC).
Statement 1: Origin
Correct. Clear cell renal cell carcinoma (ccRCC), the most common subtype, originates from the epithelium of the proximal convoluted tubule.
Statement 2: Gender Preponderance
Incorrect. Renal cell carcinoma typically affects males more frequently than females, exhibiting a male preponderance.
Statement 3: Major Subtypes
Correct. The primary histological subtypes of RCC include clear cell, papillary, and chromophobe types.
Statement 4: Treatment for Localized Disease
Correct. For organ-confined (localized) renal cell carcinoma, surgery, such as partial or radical nephrectomy, is the primary and most effective treatment modality.
Conclusion
Based on the analysis, statements 1, 3, and 4 are correct. Statement 2 is incorrect.
Therefore, the correct combination is 1, 3, and 4.
Important Questions from Urinary System & Surgical Disorders
- A 20 years old man had history of pain in the right side of abdomen. His X-ray abdomen AP view shows radio-opaque shadow, which on lateral film falls behind the vertebral column. The probable diagnosis is:
- Urinary bladder can be injured in all of the following operations EXCEPT:
- Which of the following are correct about ectopic ureters ?
1. They are more common in males
2. They drain the upper pole of kidney
3. They are associated with duplex ureter
4. They may cause incontinence
Select the correct answer using the code given below : Which of the following are features of autosomal dominant polycystic kidney disease?
1. Cyst may also occur in liver, pancreas and arachnoid membrane.
2. Most commonly manifests between 20-30 years of age.
3. Clinical manifestations are renal and extrarenal.
4. Men tend to progress to renal failure more rapidly than women.
Select the correct answer using the code given below.
- Extracorporal Shock Wave Lithotripsy (ESWL) is most commonly used for the treatment of
