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Question

Which of the following statements are correct regarding renal cell carcinoma? 

1. It arises from the epithelium of the proximal convoluted tubule. 

2. It has a female preponderance. 

3. Major subtypes are clear cell, papillary and chromophobe. 

4. Surgery is the mainstay of treatment for disease. organ-confined 

Select the answer using the code given below.

The correct answer is
1, 3 and 4

Renal Cell Carcinoma Statements Analysis

This solution analyzes the correctness of four statements regarding renal cell carcinoma (RCC).

Statement 1: Origin

Correct. Clear cell renal cell carcinoma (ccRCC), the most common subtype, originates from the epithelium of the proximal convoluted tubule.

Statement 2: Gender Preponderance

Incorrect. Renal cell carcinoma typically affects males more frequently than females, exhibiting a male preponderance.

Statement 3: Major Subtypes

Correct. The primary histological subtypes of RCC include clear cell, papillary, and chromophobe types.

Statement 4: Treatment for Localized Disease

Correct. For organ-confined (localized) renal cell carcinoma, surgery, such as partial or radical nephrectomy, is the primary and most effective treatment modality.

Conclusion

Based on the analysis, statements 1, 3, and 4 are correct. Statement 2 is incorrect.

Therefore, the correct combination is 1, 3, and 4.

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Important Questions from Urinary System & Surgical Disorders

  1. Which of the following are features of autosomal dominant polycystic kidney disease? 

    1. Cyst may also occur in liver, pancreas and arachnoid membrane. 

    2. Most commonly manifests between 20-30 years of age. 

    3. Clinical manifestations are renal and extrarenal. 

    4. Men tend to progress to renal failure more rapidly than women. 

    Select the correct answer using the code given below.

  2. Extracorporal Shock Wave Lithotripsy (ESWL) is most commonly used for the treatment of
  3. Which of the following are correct regarding pathology of stress urinary incontinence? 

    1. Hypermobility of urethra 

    2. Ascend of bladder neck and proximal urethra above diaphragm 

    3. Lowered urethral pressure 

    4. Increased detrusor activity 

    Select the answer using the code given below.

  4. Which of the following are correct about ectopic ureters ? 

    1. They are more common in males 

    2. They drain the upper pole of kidney 

    3. They are associated with duplex ureter 

    4. They may cause incontinence 

    Select the correct answer using the code given below :

  5. Anderson-Hynes plasty is a type of repair of
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