Which of the following drugs is/are useful in the treatment of Listeria monocytogenes infection? 1. Ceftriaxone 2. Gentamicin 3. Ampicillin 4. Sulfamethoxazole Select the correct answer using the code given below.
Listeria monocytogenes Infection Treatment
The treatment of Listeria monocytogenes infections requires specific antibiotic choices. Evaluating the efficacy of the listed drugs is crucial for selecting the correct treatment regimen.
Drug Efficacy Assessment
- Ampicillin: It is considered a first-line treatment for infections caused by Listeria monocytogenes due to its proven effectiveness.
- Gentamicin: This aminoglycoside antibiotic is often used in combination with beta-lactam antibiotics like Ampicillin. This combination provides synergistic activity, particularly beneficial for severe or complicated listeriosis.
- Sulfamethoxazole: Often administered as part of Trimethoprim/Sulfamethoxazole (TMP-SMX), this combination serves as an important alternative treatment for listeriosis, especially in patients with penicillin allergies.
- Ceftriaxone: Cephalosporins, including Ceftriaxone, are generally considered less effective against Listeria monocytogenes compared to penicillins or other agents. Their use is typically avoided as a primary treatment.
Conclusion on Useful Drugs
Based on established treatment guidelines:
- Ampicillin (3) is effective.
- Gentamicin (2) is useful, often in combination therapy.
- Sulfamethoxazole (4) is a viable alternative.
- Ceftriaxone (1) is generally not recommended as a primary treatment.
Therefore, drugs 2, 3, and 4 are considered useful in treating Listeria monocytogenes infection.
Important Questions from Bacterial Infections
Which of the following are major criteria under the Jones Criteria for Acute Rheumatic Fever?
1. Chorea
2. Erythema Marginatum
3. Subcutaneous Nodules
4. Polyarthralgia
Select the correct answer using the code given below:
- Whipple's disease is characterized by the infiltration of small intestinal mucosa by 'foamy' macrophages. Which one of the following histological stains is characteristically used to stain them?
- A young male presented with recent onset urethral discharge and dysuria. On examination, the discharge was profuse and purulent. Microscopy of smears from the discharge revealed Gram-negative diplococci. What is the likely diagnosis?
- Cat-scratch disease is caused by infection of which of the following organisms?
Which of the following statements are correct regarding brucellosis?
1. Fever may develop into an undulating pattern that persists for weeks.
2. Associated musculoskeletal symptoms are a feature of the disease.
3. Brucellae behave as facultative intracellular parasites.
Select the correct answer using the code given below.
