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Question

Which of the following are major criteria under the Jones Criteria for Acute Rheumatic Fever? 

1. Chorea 

2. Erythema Marginatum 

3. Subcutaneous Nodules 

4. Polyarthralgia 

Select the correct answer using the code given below:

The correct answer is
1, 2 and 3

Jones Criteria for Acute Rheumatic Fever Diagnosis

The Jones Criteria are guidelines used to diagnose Acute Rheumatic Fever (ARF). Diagnosis typically requires evidence of a preceding streptococcal infection plus either two major criteria or one major criterion and two minor criteria.

Major Criteria Analysis

Let's examine the items listed in the question based on the established major criteria for ARF:

  • 1. Chorea: This refers to Sydenham's chorea, characterized by involuntary, purposeless movements. It is considered a major criterion.
  • 2. Erythema Marginatum: This is a distinctive rash with pale centers and serrated edges. It is considered a major criterion.
  • 3. Subcutaneous Nodules: These are firm, painless lumps found under the skin, typically over bony prominences. They are considered a major criterion.
  • 4. Polyarthralgia: This refers to joint pain without objective signs of inflammation (like swelling or warmth). While joint pain can occur, the major criterion is Polyarthritis (inflammation of multiple joints). Polyarthralgia alone is usually classified as a minor criterion.

Identifying Correct Combination

Based on the analysis, Chorea (1), Erythema Marginatum (2), and Subcutaneous Nodules (3) are all recognized major criteria. Polyarthralgia (4) is not a major criterion.

Therefore, the combination representing major criteria is 1, 2, and 3.

Conclusion

The correct option includes Chorea, Erythema Marginatum, and Subcutaneous Nodules.

Item Number Criterion Jones Criteria Status
1 Chorea Major
2 Erythema Marginatum Major
3 Subcutaneous Nodules Major
4 Polyarthralgia Minor (Polyarthritis is Major)

The correct answer combines items 1, 2, and 3.

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Important Questions from Bacterial Infections

  1. A 21-year young man presents in emergency with high grade fever with inflammation of knee and ankle joints which is fleeting in nature. There is history of occasional palpitations. There is no history of antecedent sore throat. On examination, splenomegaly is present. The ECG shows prolongation of PR interval. What is the most likely diagnosis in India?
  2. Long term use of proton pump inhibitor in elderly puts the patient at risk of which of the following?
    1. Community acquired pneumonia
    2. Clostridium difficile associated disease
    3. Urinary tract infection
    Select the correct answer using the code given below:
  3. Which of the following features are characteristics of Whipple disease?
    1. Migratory small joint arthropathy
    2. Diarrhoea with steatorrhea
    3. Weight loss with Arthralgia
    4. Ophthalmic and CNS symptoms
    Select the correct answer using the code given below:
  4. Which of the following infections does NOT cause cold antibodies immune haemolysis?
  5. A 22-year old male is admitted with fever and altered consciousness for two days. Examination reveals nuchal rigidity and diffuse petechial rash on the trunk and lower extremities. The most likely etiologic agent is:
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