The major products E and F in the following reaction sequence are 
The question involves a reaction sequence, and we need to determine the major products E and F.
Let's break down the reaction:
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The starting material is an aromatic aldehyde.
First step: Reaction with the Wittig reagent (triphenylphosphonium ylide) generated from Br(CH2)4Br using NaH in THF:
- The ylide attacks the carbonyl carbon of the aldehyde.
- This forms an alkene, leading to product E. This is a typical Wittig reaction.
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Product E: An alkene without substitution on the new double bond.
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Second step: Epoxidation and rearrangement using m-CPBA (meta-chloroperoxybenzoic acid) followed by BF3.OEt2:
- m-CPBA transforms the alkene into an epoxide.
- BF3.OEt2 induces epoxide opening and rearrangement to give product F.
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Product F: The rearranged product, including a cyclized ether ring.
Therefore, the major products E and F correspond to the first option given in the choices.
This matches the correct answer shown in the options.
Important Questions from Organic Synthesis
The major products X and Y formed in the following reaction sequences are
For the following reaction, the possible product(s) is/are
The reaction(s) that yield(s) X as the major product is (are)
Consider the following reaction sequence. The correct option(s) is (are)
In the given reaction sequence, the amount of R produced (in g) is ________.
(Given: molar mass (in g $mol^{-1}$) of H = 1, C = 12, N = 14, O = 16, and S = 32)
(rounded off to two decimal places)
