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Question

The major product of the following reaction is

The correct answer is

The given reaction involves a carbohydrate derivative reacting with dimethyl sulfate (\text{Me}_2\text{SO}_4) in the presence of sodium hydroxide (NaOH), followed by acidic hydrolysis with hydrochloric acid (HCl) and water.

Step-by-Step Reaction Explanation:

  1. The reaction begins with \text{Me}_2\text{SO}_4 acting as a methylating agent. This will methylate the hydroxyl groups available on the carbohydrate molecule.
  2. NaOH facilitates the deprotonation of OH groups, making them more nucleophilic, which aids in the methylation process.
  3. All primary and secondary alcohol groups in the carbohydrate are converted to methyl ethers, except for the ketal formation (acetal linkages) typically unaltered in neutral/basic conditions.
  4. In the second step, acid hydrolysis (using HCl and H2O) results in breaking down any acetal formed (if applicable), restoring any hemiacetal to aldehyde if initially present. This reaction, however, is aimed at simply methylating without altering the primary sugar structure significantly.

Therefore, the most significant structural change is the conversion of free OH groups into OCH3.

Conclusion:

The major product is the full methylated derivative of the carbohydrate, preserving the ring structure but converting each available hydroxyl group to a methoxy group.

Correct reaction product

This corresponds to the given correct answer option.

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Important Questions from Organic Transformations

  1. The major products X and Y in the following reaction sequence are 

  2. The following conversion is an example of 

  3. The major product formed in the reaction given below is

  4. In the following reaction 

    the major product [X] is

  5. In the following reaction 

    the major product [X] is

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