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Question

The mainstay treatment of bipolar disorders is:

The correct answer is
Lithium

Bipolar Disorder Mainstay Treatment

The established **mainstay treatment** for **bipolar disorders** is typically a mood stabilizer. Let's review the options:

Evaluating Treatment Options

  • Lithium: This medication is widely recognized as the gold standard and the most effective long-term treatment for stabilizing mood in bipolar disorder, effectively reducing the frequency and intensity of both manic and depressive episodes. It is considered the mainstay therapy.
  • Oxcarbazine: While an anticonvulsant, it is sometimes used as a mood stabilizer, but it's generally not considered the primary mainstay compared to lithium, especially for classic bipolar disorder.
  • Risperidone and Olanzapine: These are antipsychotic medications. They are often used to manage acute manic episodes or psychotic symptoms associated with bipolar disorder, or sometimes as add-on therapy, but they are not the foundational mainstay treatment for long-term mood stabilization.

Conclusion on Mainstay Therapy

Based on clinical evidence and practice guidelines, Lithium remains the cornerstone medication for the maintenance treatment of bipolar disorder, making it the clear mainstay.

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Important Questions from Bipolar Disorder

  1. Long term treatment of bipolar disorder with lithium carbonate can cause which of the following adverse effects ? 

    1. Weight loss 

    2. Hypothyroidism 

    3. Increased levels of parathyroid hormone 

    4. Nephrogenic diabetes insipidus 

    Select the correct answer using the code given below:

  2. Which of the following are classified as mood-stabilising psychotropic drugs? 

    1. Lithium 

    2. Valproate 

    3. Lamotrigine 

    Select the correct answer using the code given below:

  3. Lithium carbonate is employed in the following conditions except:
  4. Match List I with List II and select the correct answer using the code given below the lists :

    List I (Disease)List II (Drug)
    A. Bipolar disorder1. Clomipramine
    B. Major depression2. Clozapine
    C. Schizophrenia3. Venlafaxine
    D. Obsessive compulsive disorder4. Lithium

    Code :

  5. Lithium is the drug of choice for the treatment of
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