The given Vit-B12-dependent isomerization is catalyzed by the enzyme
glycerol dehydratase
Coenzyme B12 (adenosylcobalamin) enzymes use homolysis of the Co–C bond to make a 5′-deoxyadenosyl radical, which abstracts a hydrogen atom from the substrate and starts a 1,2-rearrangement in which a group exchanges places with a hydrogen on the adjacent carbon.
The scheme shows glycerol, HOCH2CH(OH)CH2OH, converted into 3-hydroxypropanal and water. The 1,2-shift of an OH gives a gem-diol, which loses water to form the aldehyde. This dehydration of glycerol is catalysed by glycerol dehydratase (as in Klebsiella and Citrobacter, en route to 1,3-propanediol).
Diol dehydratase catalyses the analogous conversion of 1,2-propanediol into propanal, not the reaction of the triol. Glutamate mutase rearranges the carbon skeleton of glutamate to 3-methylaspartate. Glyceraldehyde synthase is not a B12-dependent enzyme and does not produce 3-hydroxypropanal.
glycerol dehydratase option is correct.
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Important Questions from Mixed Topic (MH-SET)
.................... is a client server application that identifies each host on the internet with a unique user-friendly name.
Every OS has a ................ or .......... which primarily resides in the main memory of the computer to perform some of the basic functions of the OS.
(i) Kernel
(ii) Interface
(iii) Nucleus
(iv) Compiler
Codes:
Which of the following are referred to as low level language?
(i) Machine language
(ii) Assembly language
(iii) High level language
(iv) Natural language
Codes:
Match the following:
List I List II (a) New York Public Library (i) Shelv AR (b) Miami University Augmented Research Group (ii) Smart library (c) Oula University Library (iii) Wolf Walk (d) North Carolina State University (iv) Find the future Codes:
Which part of the QR code represents the encoded data?
