Metastasis Definition and Process
Metastasis is the key characteristic of malignant tumors that describes the process where cancer cells invade surrounding tissues, enter the bloodstream or lymphatic system, and travel to distant parts of the body to form new secondary tumors.
This ability involves several steps:
- Detachment: Cancer cells break away from the primary tumor.
- Invasion: Cells invade nearby tissues and blood/lymphatic vessels.
- Circulation: Cells travel through the circulatory or lymphatic system.
- Arrest and Extravasation: Cells lodge in a new organ or tissue and exit the vessel.
- Formation of Secondary Tumor: Cells multiply to form a new tumor at the distant site.
Distinguishing Metastasis from Other Terms
It's important to differentiate metastasis from other related terms:
- Etiologic: Refers to the cause or origin of a disease, not the spread.
- Anaplasia: Refers to the loss of differentiation of cells and their normal appearance, a characteristic of malignancy but not the spread itself.
- Hyperplasia: Refers to an increase in the number of cells in an organ or tissue, often a benign response to a stimulus, unlike malignant spread.
Therefore, the specific ability of a malignant cell to detach and establish a new tumor elsewhere is termed metastasis.
Similar Questions
- Choose the correct sequence for how a type I topoisomerase relaxes DNA.
A. DNA release
B. Cleavage and opening of gate
C. Rejoining of cleaved strand
D. Strand passage
Choose the correct answer from the options given below : - Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : Cells of different tissues essentially require $CO_2$ to generate energy and perform metabolic functions.
Reason (R) : Deficiency of oxygen or hypoxia results in failure to carry metabolic functions.
In the light of the above statements, choose the most appropriate answer from the options given below : - Depending upon the antigen how much lag period is required for memory B cell after antigen administration.
- Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : The conduction in the Atrio-ventricular (AV) node is slow i.e. 0.05 m/sec, there is a delay of approx. 0.1 second before excitation spreads to the ventricles.
Reason (R) : AV node delay enables the atria to empty the blood present within them into the ventricles before these contract.
In the light of the above statements, choose the most appropriate answer from the options given below : - Choose the correct sequence of the structure of the ear starting from external ear (entry of sound) to inner ear.
A. Helix
B. Oval window
C. Pinna
D. Cochlae
E. Tympanic membrane
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A. Aorta
B. Aortic valve
C. Left ventricle
D. Superior and inferior venae cavae
E. Right atrium
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Assertion (A) : Lysosomes are called suicidal bags.
Reason (R) : When a cell dies, lysosomal enzymes cause autolysis of the remanant.
In the light of the above statements, choose the most appropriate answer from the options given below : - Which of the following wavelength (nm) correspond to visible range of humans ?
A. 20 nm
B. 200 nm
C. 400 nm
D. 600 nm
E. 900 nm
Choose the correct answer from the options given below : - Which of the following advantages of chemiluminescence technology are true :
A. Low cost
B. Non linearity
C. Stability
D. Sensitivity
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Important Questions from Mixed Topic (CUET PG)
- Who was the founder of Bolshevik Communist party?
- What is the key guide to statecraft in the realist tradition?
- Chronologically arrange the events in the Cold War period.
A. Berlin Wall is constructed
B. Communist China joins the UN
C. Soviet invasion of Czechoslovakia
D. Berlin Blockade
Choose the correct answer from the options given below: Morgenthau's principles of political realism are:
A. Politics is rooted in permanent and unchanging human nature which is basically self centred, self-regarding and self-interested
B. Politics is an autonomous sphere of action and cannot therefore be reduced to morals
C. International Politics is an arena of conflicting self-interests
D. The ethics of international relations is situational ethics which is very different from private morality
Choose the correct answer from the options given below:Who among the following political thinkers consider the anarchical self help system to be a compelling factor for States to maximise their relative power positions?
