Subacute sclerosing panencephalitis (SSPE) is a rare and fatal neurological disease that affects the central nervous system. It is known to be a delayed complication primarily resulting from infection with the Measles virus.
SSPE Causative Agent Identification
The association between SSPE and specific viral infections is well-established:
- Measles Virus: SSPE is widely recognized as a late sequela of measles virus infection, particularly when the initial infection occurs in early childhood. The measles virus persists in the brain, leading to chronic inflammation and neurodegeneration over many years.
- Mumps Virus: Mumps virus causes mumps and associated complications like meningitis or orchitis but is not linked to SSPE.
- Exanthema subitum: Also known as Roseola infantum, this condition is caused by Human Herpesvirus 6 (HHV-6) and does not cause SSPE.
- Erythema infectiosum: Caused by Parvovirus B19, this illness (Fifth disease) does not lead to SSPE.
Conclusion on SSPE Link
Therefore, the specific viral infection associated with Subacute sclerosing panencephalitis is Measles.
Important Questions from Viral Infections
- A 'slapped cheek' rash is characteristically seen in which of the following infections?
HIV-associated neurocognitive disorder (HAND) includes which of the following?
1. Asymptomatic neurocognitive disorder
2. Minor neurocognitive disorder
3. HIV-associated dementia
Select the correct answer using the code given below.
Which of the following treatments for a pregnant lady who has been exposed to a patient of chicken pox are correct?
1. Varicella-zoster immune globulin
2. Varicella-zoster vaccine
3. Acyclovir
4. Prednisolone
Select the correct answer using the code given below.
Which of the following statements are correct regarding Kyasanur forest disease?
1. It is commonly seen in North-Eastern States of India.
2. Monkeys act as reservoir of the disease.
3. Transmission happens through tick bite.
4. Inactivated vaccine is available for its prevention.
Select the correct answer using the code given below.
- Which one of the following has the highest risk of human immunodeficiency virus (HIV) transmission after single exposure to an HIV-infected source ?
