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Question

Match List-I with List-II:

List-I (Scientists)

List-II (Discovery)

List-IList-II
(A) Sutton and Boveri(I) X-Body
(B) Sturtevant(II) Chromosomal Theory of Inheritance
(C) Henking(III) Transformation in bacteria
(D) Griffith(IV) Genetic maps

Choose the correct answer from the options given below:

The correct answer is

(A) - (II), (B) - (IV), (C) - (I), (D) - (III)

Matching Scientists with Key Genetics Discoveries

This question asks us to match famous scientists from the field of genetics with their significant discoveries or contributions. Let's examine each scientist and their work provided in the lists.

Analyzing List-I Scientists and List-II Discoveries

We have four scientists in List-I and four discoveries in List-II:

List-I (Scientists):

  • (A) Sutton and Boveri
  • (B) Sturtevant
  • (C) Henking
  • (D) Griffith

List-II (Discovery):

  • (I) X-Body
  • (II) Chromosomal Theory of Inheritance
  • (III) Transformation in bacteria
  • (IV) Genetic maps

Step-by-Step Matching Process

Let's consider each scientist and link them to their correct discovery:

  1. (A) Sutton and Boveri: Walter Sutton and Theodor Boveri independently proposed that chromosomes are the carriers of genetic information. Their work laid the foundation for the Chromosomal Theory of Inheritance, which states that Mendelian factors (genes) are located on chromosomes.
    Therefore, (A) matches with (II).
  2. (B) Sturtevant: Alfred Sturtevant, a student of Thomas Hunt Morgan, used the concept of recombination frequency between genes on a chromosome to determine their relative positions. This led to the development of the first Genetic maps, which show the linear arrangement of genes on a chromosome.
    Therefore, (B) matches with (IV).
  3. (C) Henking: Hermann Henking, while studying spermatogenesis in the firefly Pyrrhocoris apterus in 1891, observed a nuclear structure that he called the 'X-body'. This structure was later identified as the X-chromosome and was linked to sex determination.
    Therefore, (C) matches with (I).
  4. (D) Griffith: Frederick Griffith conducted experiments in 1928 using Streptococcus pneumoniae bacteria. His experiment demonstrated that a substance from virulent bacteria could transform harmless bacteria into virulent ones. This phenomenon was called Transformation in bacteria, which later provided evidence that DNA was the genetic material.
    Therefore, (D) matches with (III).

Summary of Matches

Based on the analysis, the correct matches are:

  • (A) - (II)
  • (B) - (IV)
  • (C) - (I)
  • (D) - (III)

Tabular Representation of the Matching

List-I (Scientists) List-II (Discovery) Match
(A) Sutton and Boveri (I) X-Body (A) matches (II)
(B) Sturtevant (II) Chromosomal Theory of Inheritance (B) matches (IV)
(C) Henking (III) Transformation in bacteria (C) matches (I)
(D) Griffith (IV) Genetic maps (D) matches (III)

The combination that represents the correct matches is (A) - (II), (B) - (IV), (C) - (I), (D) - (III).

Revision Table: Scientists and Genetics Discoveries

Scientist(s) Key Discovery/Contribution
Sutton and Boveri Chromosomal Theory of Inheritance
Sturtevant Construction of first Genetic maps
Henking Discovery of the X-Body (related to sex determination)
Griffith Demonstration of Transformation in bacteria

Additional Information on Genetics Concepts

Understanding these discoveries is fundamental to the study of genetics:

  • Chromosomal Theory of Inheritance: This theory unified Mendelian genetics with chromosome behavior during meiosis, explaining how traits are inherited through chromosomes. It was a crucial step in establishing chromosomes as the physical basis of heredity.
  • Genetic Maps: These maps show the relative locations of genes along a chromosome, based on recombination frequencies. They are essential tools for gene mapping, understanding chromosome structure, and studying evolutionary relationships.
  • X-Body/Sex Chromosomes: The discovery of the X-body by Henking led to the identification of sex chromosomes (X and Y) and our understanding of the chromosomal basis of sex determination in many organisms.
  • Bacterial Transformation: Griffith's experiment showed that genetic material could be transferred between bacterial cells. This paved the way for the identification of DNA as the genetic material by Avery, MacLeod, and McCarty, and is a key mechanism for genetic variation in bacteria.
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Similar Questions

  1. Which of the following statements are incorrect with respect to nucleotides?

    (A) Purines and pyrimidines are nitrogenous bases.

    (B) Nucleotides are non-enzymatic molecules.

    (C) Phosphate group is linked to –OH of 5' C of a nucleoside through phosphoester linkage.

    (D) In RNA, every nucleotide residue has an additional –OH group present at 2' position in the ribose.

    (E) Thymine is an example of pyrimidine.

  2. Arrange the given steps of DNA fingerprinting in the sequence from initiation to end:

    (A) Digestion of DNA by restriction endonuclease

    (B) Isolation of DNA

    (C) Hybridisation using labelled VNTR probe

    (D) Transferring (blotting) of separated DNA fragments to synthetic membrane

  3. Nucleosome is associated with _______ molecules of histones.

  4. Select the incorrect statement:

  5. Match List-I with List-II:

    List-I (Genes)List-II (Proteins – codes for lac operon)
    (A) ‘i’(I) permease
    (B) ‘a’(II) β-galactosidase
    (C) ‘y’(III) transacetylase
    (D) ‘z’(IV) repressor

    Choose the correct answer from the options given below:

  6. The size of VNTR varies from:

  7. Select the observations drawn from the human genome project which are correct:

    (A) The human genome contains 3164.7 million bp.

    (B) The average gene consists of 3000 bases.

    (C) Total number of genes is estimated at 30,000.

    (D) The functions are unknown for over 50% of discovered genes.

    (E) Less than 2% of the genome codes for proteins.

  8. Arrange the following steps of DNA fingerprinting in proper sequence:

    (A) Hybridisation using labelled VNTR probe

    (B) Separation of DNA fragments by electrophoresis

    (C) Digestion of DNA by restriction endonucleases

    (D) Blotting of separated DNA fragments to nylon

    (E) Isolation of DNA

    Choose the correct answer from the options given below:

  9. Nucleosome is:

  10. “Transforming Principle” was given by:


Important Questions from Molecular Basis of Inheritance

  1. Which of the following statements are incorrect with respect to nucleotides?

    (A) Purines and pyrimidines are nitrogenous bases.

    (B) Nucleotides are non-enzymatic molecules.

    (C) Phosphate group is linked to –OH of 5' C of a nucleoside through phosphoester linkage.

    (D) In RNA, every nucleotide residue has an additional –OH group present at 2' position in the ribose.

    (E) Thymine is an example of pyrimidine.

  2. Arrange the given steps of DNA fingerprinting in the sequence from initiation to end:

    (A) Digestion of DNA by restriction endonuclease

    (B) Isolation of DNA

    (C) Hybridisation using labelled VNTR probe

    (D) Transferring (blotting) of separated DNA fragments to synthetic membrane

  3. Nucleosome is associated with _______ molecules of histones.

  4. Two nucleotides linked together to form a dinucleotide through:

  5. ABO blood groups are controlled by _______.

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