Assertion (A) : Rifampicin is used to treat various bacterial infections particularly tuberculosis.
Reason (R) : It acts by disrupting the bacterial cell-wall, nuclear membrane and mitochondria.
In the light of the above statements, choose the most appropriate answer from the options given below :
Analyzing Assertion (A): Rifampicin Use
Assertion (A) states that Rifampicin is used for bacterial infections, especially tuberculosis (TB). This is medically accurate. Rifampicin is a primary antibiotic used in the treatment regimens for tuberculosis and other bacterial infections like leprosy and meningitis prophylaxis.
Evaluating Reason (R): Rifampicin's Action
Reason (R) claims Rifampicin disrupts the bacterial cell wall, nuclear membrane, and mitochondria. This statement is incorrect:
- Rifampicin's primary mechanism is inhibiting bacterial DNA-dependent RNA polymerase, stopping transcription.
- It does not target the bacterial cell wall (unlike penicillins).
- Bacteria lack a nuclear membrane; they have a nucleoid region.
- Bacteria do not possess mitochondria; this organelle is found in eukaryotic cells.
Therefore, the stated reason for Rifampicin's effectiveness is factually wrong.
Determining the Correct Option
Based on the analysis:
- Assertion (A) is correct.
- Reason (R) is incorrect.
This corresponds to the option stating that (A) is correct, but (R) is not correct.
Conclusion
The most appropriate answer is that Assertion (A) is correct, but Reason (R) is incorrect.
Similar Questions
- Primary changes in Acid Base disorders are :
A. Metabolic acidosis decreased plasma bicarbonate
B. Metabolic alkaloses decreased plasma bicarbonate
C. Respiratory alkalosis decreased $pco_{2}$
D. Respiratory acidosis decreased $pco_{2}$
Choose the correct answer from the options given below : - Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : A covlent single bonds in biological molecules have energies similar to the energy of the C-C bond in ethane.
Reason (R) : It is because less electrons are shared between atoms in double bonds they require more energy to break than single bonds.
In the light of the above statements, choose the most appropriate answer from the options given below : - A solution is called hypertonic when :
List - I shows various isotopes and List - II indicates their half-lives.
Match List - I with List - II.
List - I List - II A. ${ }^{3}\text{H}$ I. 60 days B. ${ }^{14}\text{C}$ II. 14.5 days C. ${ }^{32}\text{P}$ III. 5700 years D. ${ }^{125}\text{I}$ IV. 12.2 years
Choose the correct answer from the options given below :- Based on the position of Centromere Chromosome can be divided into 4 types :
A. Meta centric : Centromere in the middle
B. Submetacentric : Centromere at the end
C. Telocentric : Terminal Centromere
D. Acrocentric : Centromere is close to middle
Choose the correct answer from the options given below : - Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : Neurons are the functional cells in brain. Glial cells are the supporting cells of the brain.
Reason (R) : Astroglia are starshaped neuronal cells.
In the light of the above statements, choose the most appropriate answer from the options given below : - Which of the following are the correct components of PCR reation ?
A. Taq Polymerase
B. Buffer (5X)
C. Primers (F and R)
D. NTPs
E. $\\text{H}_{2}\\text{O}$
Choose the correct answer from the options given below : - List the proteins detection techniques in increasing order of sensitivity :
A. Bradford
B. Biuret
C. Lowry
Choose the correct answer from the options given below : - Match List - I with List - II.
List - I List - II A. ELISA I. Visualization of cells B. RIA II. Proteins identification C. Centrifugation III. Hormone detection D. Microscopy IV. Isolation of organelles
Choose the correct answer from the options given below : - Match List - I with List - II.
List - I List - II A. SDS-PAGE I. DNA B. Agarose gel electrophoresies II. Liquid chromatography C. Native Page III. Non-denatured proteins D. HPLC IV. proteins
Choose the correct answer from the options given below :
Important Questions from Mixed Topic (CUET PG)
- Kalpsutra, the illustrated canonical text is from:-
- The Harappan city almost exclusively devoted to craft production was-:
- Mohandas Karamchand Gandhi launched quit India movement after the failure of:-
- The "Objectives Resolution" was introduced in constituent assembly by:-
- Who among the following was not a member of the constituent assembly:-
