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Question

A veterinary doctor is bitten by a stray dog, which is classified as a category 3 bite. He has completed his pre-exposure prophylactic vaccination with human diploid cell Rabies vaccine with three doses administered on day 0, 7, 28 about 1 year back. Appropriate treatment would include which of the following?
1. Wound care
2. Antibiotics
3. Booster dose of Anti Rabies vaccine
4. Rabies immune globulin at wound site
Select the correct answer using the code given below:

The correct answer is
1, 2 and 3

Rabies Post-Exposure Prophylaxis (PEP) Decision

The patient presents with a category 3 bite from a stray dog and has a history of pre-exposure prophylactic (PrEP) vaccination (3 doses, 1 year ago).

Assessment of Treatment Components

  • 1. Wound Care: This is a critical first step for any bite wound. Thorough cleaning and disinfection help reduce the viral load at the site of inoculation.
  • 2. Antibiotics: Animal bites carry a significant risk of secondary bacterial infection. Prophylactic antibiotics are often recommended to prevent this.
  • 3. Booster Dose of Anti-Rabies Vaccine: For individuals who have previously completed PrEP, a category 3 exposure still warrants post-exposure prophylaxis. This typically involves booster doses of the rabies vaccine (e.g., on days 0 and 3) to elicit a rapid anamnestic antibody response.
  • 4. Rabies Immune Globulin (RIG): RIG is generally recommended for PEP-naive individuals with category 3 exposures. It is typically *not* administered to individuals who have completed a full course of PrEP, as their immune system is expected to respond adequately to vaccine boosters alone.

Conclusion on Appropriate Treatment

Based on current rabies prophylaxis guidelines, the appropriate management for this scenario includes:

  • Wound care
  • Antibiotics
  • Booster doses of Anti-Rabies vaccine

Therefore, options 1, 2, and 3 are indicated.

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Important Questions from Viral Infections

  1. A 'slapped cheek' rash is characteristically seen in which of the following infections?
  2. HIV-associated neurocognitive disorder (HAND) includes which of the following? 

    1. Asymptomatic neurocognitive disorder 

    2. Minor neurocognitive disorder 

    3. HIV-associated dementia 

    Select the correct answer using the code given below.

  3. Which of the following treatments for a pregnant lady who has been exposed to a patient of chicken pox are correct? 

    1. Varicella-zoster immune globulin 

    2. Varicella-zoster vaccine 

    3. Acyclovir 

    4. Prednisolone 

    Select the correct answer using the code given below.

  4. Which of the following statements are correct regarding Kyasanur forest disease? 

    1. It is commonly seen in North-Eastern States of India. 

    2. Monkeys act as reservoir of the disease. 

    3. Transmission happens through tick bite. 

    4. Inactivated vaccine is available for its prevention. 

    Select the correct answer using the code given below.

  5. Which one of the following has the highest risk of human immunodeficiency virus (HIV) transmission after single exposure to an HIV-infected source ?
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