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Question

With reference to Vitamin $\text{B}_6$, consider the following statements :
1. It is a cofactor for metabolism of many amino acids.
2. Its active form in humans is pyridoxal 5-phosphate.
Which of the statements given above is/are correct ?

The correct answer is
Both 1 and 2

Vitamin B6: Key Roles

The question asks about the functions and active form of Vitamin B6. Let's analyze the given statements:

Statement 1: Role in Amino Acid Metabolism

Statement 1 claims Vitamin B6 acts as a cofactor for the metabolism of many amino acids. This is correct. Vitamin B6, specifically in its active form, is essential for numerous enzymatic reactions involving amino acids, including transamination, decarboxylation, and racemization.

Statement 2: Active Form Identification

Statement 2 identifies the active form in humans as pyridoxal 5-phosphate. This is also correct. Pyridoxal 5'-phosphate (PLP) is the principal coenzyme form of Vitamin B6 involved in the biochemical processes mentioned above.

Conclusion on Statements

Since both statement 1 and statement 2 are accurate descriptions of Vitamin B6's functions and form, the correct option includes both.

  • Statement 1 is correct.
  • Statement 2 is correct.

Therefore, the correct answer is that both statements are correct.

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Important Questions from Vitamin B Complex Deficiency

  1. Consider the following statements regarding Wernicke-Korsakoff syndrome : 

    1. It is a rare complication of chronic alcohol misuse characterised by opthalmoplegia, ataxia and delirium. 

    2. There is damage to the mammillary bodies and dorsomedial nuclei of thalamus. 

    3. The underlying cause is deficiency of Vitamin B12 (Cobalamin). 

    4. The syndrome can also arise due to malabsorption or protracted vomiting. 

    Select the correct answer using the code given below:

  2. A 35 year old man with history of alcoholism presents with ophthalmoplegia, ataxia and global confusion. The treatment of choice for this patient is:

  3. The classical features of Wernicke's encephalopathy are the following except:
  4. Vitamin B$_{12}$ deficiency can cause the following except:
  5. Which one of the following pairs is not correctly matched?
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