1. It is a cofactor for metabolism of many amino acids.
2. Its active form in humans is pyridoxal 5-phosphate.
Which of the statements given above is/are correct ?
The question asks about the functions and active form of Vitamin B6. Let's analyze the given statements:
Statement 1 claims Vitamin B6 acts as a cofactor for the metabolism of many amino acids. This is correct. Vitamin B6, specifically in its active form, is essential for numerous enzymatic reactions involving amino acids, including transamination, decarboxylation, and racemization.
Statement 2 identifies the active form in humans as pyridoxal 5-phosphate. This is also correct. Pyridoxal 5'-phosphate (PLP) is the principal coenzyme form of Vitamin B6 involved in the biochemical processes mentioned above.
Since both statement 1 and statement 2 are accurate descriptions of Vitamin B6's functions and form, the correct option includes both.
Therefore, the correct answer is that both statements are correct.
Consider the following statements regarding Wernicke-Korsakoff syndrome :
1. It is a rare complication of chronic alcohol misuse characterised by opthalmoplegia, ataxia and delirium.
2. There is damage to the mammillary bodies and dorsomedial nuclei of thalamus.
3. The underlying cause is deficiency of Vitamin B12 (Cobalamin).
4. The syndrome can also arise due to malabsorption or protracted vomiting.
Select the correct answer using the code given below:
A 35 year old man with history of alcoholism presents with ophthalmoplegia, ataxia and global confusion. The treatment of choice for this patient is: