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Question

With reference to Vitamin $\text{B}_6$, consider the following statements :
1. It is a cofactor for metabolism of many amino acids.
2. Its active form in humans is pyridoxal 5-phosphate.
Which of the statements given above is/are correct ?

The correct answer is
Both 1 and 2

Vitamin B6: Key Roles

The question asks about the functions and active form of Vitamin B6. Let's analyze the given statements:

Statement 1: Role in Amino Acid Metabolism

Statement 1 claims Vitamin B6 acts as a cofactor for the metabolism of many amino acids. This is correct. Vitamin B6, specifically in its active form, is essential for numerous enzymatic reactions involving amino acids, including transamination, decarboxylation, and racemization.

Statement 2: Active Form Identification

Statement 2 identifies the active form in humans as pyridoxal 5-phosphate. This is also correct. Pyridoxal 5'-phosphate (PLP) is the principal coenzyme form of Vitamin B6 involved in the biochemical processes mentioned above.

Conclusion on Statements

Since both statement 1 and statement 2 are accurate descriptions of Vitamin B6's functions and form, the correct option includes both.

  • Statement 1 is correct.
  • Statement 2 is correct.

Therefore, the correct answer is that both statements are correct.

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Important Questions from Vitamin B Complex Deficiency

  1. All of the following cause dementia EXCEPT:
  2. Which of the following is/are neurological manifestation(s) of vitamin $B_{12}$ deficiency?
    1. Poor memory
    2. Optic atrophy
    3. Personality change
    Select the correct answer using the code given below:
  3. Angular stomatitis and cheilosis are indicative of deficiencies of which of the following vitamins?
    1. Riboflavin
    2. Pyridoxine
    3. Thiamine
    4. Niacin
    Select the correct answer using the code given below:
  4. Confabulation is a feature of the deficiency of:
  5. All of the following are components of the Wernicke's syndrome EXCEPT:
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