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Question

Which one of the following pairs is not correctly matched?

The correct answer is
Starvation ketosis - Glucagon

Analyzing Medical Condition Pairs

The question requires identifying the pair that is not correctly matched, typically linking a condition with its management, a cause, or a related physiological factor.

Option 1: Uraemic acidosis - Haemodialysis

This pair is correctly matched. Uraemic acidosis is a metabolic complication of chronic kidney disease. Haemodialysis is a primary treatment used to correct acid-base imbalances and remove toxins in patients with kidney failure.

Option 2: Methanol intoxication - Ethanol

This pair is correctly matched. Ethanol (drinking alcohol) serves as a competitive inhibitor of alcohol dehydrogenase, the enzyme that metabolizes methanol. By administering ethanol, the metabolism of toxic methanol is slowed, preventing the formation of harmful byproducts like formic acid.

Option 3: Hyperosmolar coma - Intravenous fluids

This pair is correctly matched. Hyperosmolar coma, often seen in uncontrolled diabetes (Hyperosmolar Hyperglycemic State - HHS), is characterized by severe dehydration and hyperglycemia. Rapid rehydration with intravenous fluids is a critical first step in treatment.

Option 4: Starvation ketosis - Glucagon

This pair is considered incorrectly matched in the context of condition-treatment or direct cause-effect pairing. Starvation ketosis is a metabolic state where the body produces ketones from fat breakdown due to prolonged lack of carbohydrates. While glucagon levels rise during fasting and stimulate lipolysis and ketogenesis, glucagon itself is not a direct treatment or antidote for starvation ketosis. It is a hormone involved in the physiological response to fasting, rather than a management strategy like the treatments in the other options.

Conclusion

Based on the analysis, the pair 'Starvation ketosis - Glucagon' is the one that is not correctly matched in the typical sense of condition-management or condition-treatment.

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Important Questions from Acid-Base Disorders

  1. The most common acid-base disturbance in critically ill patients is :
  2. Salicylate intoxication in adults usually causes:
    1. Severe respiratory alkalosis.
    2. Mixed metabolic acidosis respiratory alkalosis.
    3. Hyperchloremic metabolic acidosis.
    Select the correct answer using the code given below
  3. Consider the following:
    1. Normal anion gap
    2. Hyperchloraemic acidosis
    3. Inappropriately high urinary pH (>5.4)
    Which of the above are the characteristic features of renal tubular acidosis (RTA)?

  4. Which one of the following is not an example of metabolic acidosis with high anion gap?
  5. Consider the following statements regarding distal renal tubular acidosis:
    1. Blood biochemistry reveals normal anion gap metabolic acidosis
    2. There is defective secretion of H$^+$ in the distal tubule.
    3. There may be associated muscle weakness and rickets.
    4. Children may present with polydipsia and polyuria.
    Which of the above statements are correct?
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