Identifying Non-Characteristic of Vitamin D Resistant Rickets
Vitamin-D resistant rickets encompasses a group of inherited disorders affecting phosphate and calcium metabolism. Understanding the typical features helps differentiate associated conditions.
Characteristics of Vitamin-D Resistant Rickets
- Hypophosphatemia: This is a defining feature, indicating low levels of phosphate in the blood due to impaired kidney reabsorption.
- Reduced Calcium Absorption: The condition often involves problems with vitamin D activation or function, leading to less calcium being absorbed from the gut. This contributes to bone softening.
- X-linked Inheritance: Many forms, notably X-linked hypophosphatemic rickets (XLH), follow an X-linked inheritance pattern, meaning the gene responsible is located on the X chromosome.
Why Renal Stones Are Not Characteristic
Renal stones (kidney stones) are typically associated with conditions involving high levels of calcium or other stone-forming substances in the urine. In Vitamin-D resistant rickets, the primary metabolic disturbance is related to phosphate. While calcium levels might be affected secondarily, the formation of renal stones is not a primary or common characteristic of this disorder, unlike the other listed features.
Important Questions from Vitamin D Deficiency
Consider the following statements with regard to Vitamin D deficiency :
1. Vitamin D deficiency is common in northern latitudes.
2. Vitamin D deficiency is more likely to develop in people with dark skin.
3. Exposure to UV light is advisable in patients with Vitamin D deficiency.
Which of the statements given above are correct?
Which of the following abnormalities occur from vitamin D deficiency in children?
1. Craniotabes
2. Bossing of frontal and parietal bones
3. Muscle hypotonia
4. Shrinking of epiphysis at the lower end of radius
Select the correct answer using the code given below.
- Which one of the following is not a feature of vitamin D deficiency rickets?
- What is the naturally occurring form of vitamin D in the human skin ?
