Question
Which one of the following is not a useful drug for the initial management of a case with status epilepticus?
The correct answer is
IV clobazam
Initial Status Epilepticus Management Drug Choice
Effective initial management of status epilepticus prioritizes rapid seizure termination. Standard protocols include:
- First-line: Immediate IV benzodiazepines (e.g., lorazepam, diazepam).
- Second-line: IV anti-epileptic drugs (AEDs) such as phenytoin or sodium valproate if seizures persist.
- Third-line: Anesthetic agents reserved for refractory cases.
Evaluating Drug Usefulness
- IV Phenytoin (Option 1) and IV Sodium Valproate (Option 4) are established second-line agents, playing a key role after initial benzodiazepine failure. They are considered useful for initial management steps.
- IV Thiopental (Option 3) is indicated for refractory status epilepticus, not initial treatment.
- IV Clobazam (Option 2), despite being a benzodiazepine, is not the standard choice for initial IV emergency stabilization in generalized status epilepticus. Compared to lorazepam or diazepam, its role in this critical phase is less defined. Consequently, it is considered the drug least suitable for the initial management phase among the options provided.
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Important Questions from Epilepsy
Consider the following with regard to trigger factors for seizures :
1. Flickering lights
2. Recreational drug misuse
3. Non-compliance to treatment with antiepileptic drugs
4. Sleep deprivation
Which of the factors given above are correct?
Focal seizures may be associated with which of the following?
1. Jacksonian march
2. Todd's paralysis
3. Epilepsia partialis continua
Select the correct answer using the code given below.
- Typical absence seizures are characterized by
- In a young epileptic woman wishing to use oral contraceptive agents, which of the following drugs is not an ideal agent?
- Which of the following is not useful in the management of status epilepticus?
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