Understanding Monosomy X Chromosome
The question asks to identify the condition caused by the monosomy of the X chromosome. Monosomy means having only one copy of a specific chromosome instead of the usual pair. Monosomy of the X chromosome refers to the condition where an individual has only one X chromosome, often represented as '$XO$'.
Analyzing the Options
- Adrenogenital syndrome: This relates to genetic disorders affecting the adrenal glands and hormone production, not directly caused by X chromosome monosomy.
- Testicular feminization (Androgen Insensitivity Syndrome): This occurs in individuals with an XY (male) genotype who are insensitive to androgens. It is not caused by monosomy X.
- Turner's syndrome: This is a genetic condition that affects females and results from a missing or partially missing X chromosome. The typical karyotype is '$XO$'. This directly matches the definition of monosomy of the X chromosome.
- Klinefelter's syndrome: This condition affects males and is characterized by the presence of an extra X chromosome, resulting in a karyotype such as '$XXY$'. This is a form of aneuploidy but not monosomy of the X chromosome.
Identifying the Correct Condition
Based on the analysis, Turner's syndrome is the condition resulting from the monosomy of the X chromosome ('$XO$').
Important Questions from Genetic Disorders & Public Health
- Which one of the following conditions is NOT inborn error of metabolism?
- Amniocentesis is called for in all of the following circumstances EXCEPT:
- Consider the following pairs of genetic diseases that show Mendelian inheritance. Each of the following pairs represents a genetic disease and it has been matched with a type of inheritance :How many of the pairs given above are correctly matched?
1 Cystic fibrosis Autosomal recessive 2 Huntington's chorea Autosomal dominant 3 Marfan's syndrome Recessive sex-linked Consider the following statements :
Statement I:
Signs of thalassemia major usually develop after 6 months of age.
Statement II:
This is the time when haemoglobin synthesis switches from haemo-globin F to haemoglobin A.
Which one of the following is correct in respect of the above statements?
- Cystic fibrosis involves which of the following organs?
1. Lungs
2. Liver
3. Pancreas
4. Kidney
Select the correct answer using the code given below.
