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Question

Which of the following statements regarding Paget's disease of nipple are correct?
1. It represents benign pathology of nipple areola complex
2. It is eczema like condition of nipple and areola
3. Erosion of nipple is seen
4. Nipple biopsy is required for definitive diagnosis
Select the correct answer using the code given below:

The correct answer is
2, 3 and 4

Paget's Disease Nipple Statements Analysis

This question asks to identify the correct statements describing Paget's disease of the nipple.

Statement Evaluation

  • Statement 1: It represents benign pathology of nipple areola complex
    This statement is incorrect. Paget's disease of the nipple is a malignant condition, often associated with underlying breast cancer (ductal carcinoma in situ or invasive carcinoma). It is not benign.
  • Statement 2: It is eczema like condition of nipple and areola
    This statement is correct. Clinically, Paget's disease often mimics eczema, presenting as a red, scaly, itchy rash on the nipple and surrounding areola.
  • Statement 3: Erosion of nipple is seen
    This statement is correct. The characteristic skin changes can progress to include crusting, ulceration, and erosion of the nipple.
  • Statement 4: Nipple biopsy is required for definitive diagnosis
    This statement is correct. While the symptoms can suggest the condition, a biopsy of the affected nipple and areola tissue is necessary to confirm the presence of Paget cells and establish a definitive diagnosis.

Conclusion

Based on the analysis, statements 2, 3, and 4 are correct descriptions of Paget's disease of the nipple.

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