Question
Which of the following statements are correct in respect of haemophilia?
1. It is hereditary bleeding disorder.
2. It has a higher incidence among Asians.
3. It affects females occasionally and mildly.
Select the correct answer using the code given below.
The correct answer is
1 and 3 only
To determine the correct answer, let's evaluate each statement in relation to haemophilia:
- Statement 1: It is a hereditary bleeding disorder.
- This statement is correct. Haemophilia is indeed a hereditary disorder caused by a genetic mutation, leading to a deficiency in the blood's ability to clot properly. It typically involves the sex chromosomes and is passed from parents to children.
- Statement 2: It has a higher incidence among Asians.
- This statement is incorrect. Haemophilia does not have a higher incidence among Asians. It is a genetic disorder that equally affects people across all ethnic backgrounds.
- Statement 3: It affects females occasionally and mildly.
- This statement can be considered correct. While haemophilia predominantly affects males (as it is X-linked recessive), females can be carriers and occasionally exhibit mild symptoms due to lyonization or X-chromosome inactivation. However, it is very rare for females to be severely affected.
Based on the analysis above, statements 1 and 3 are correct. Therefore, the correct answer is 1 and 3 only.
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Important Questions from Genetic Disorders & Public Health
- Which one of the following conditions is NOT inborn error of metabolism?
- Amniocentesis is called for in all of the following circumstances EXCEPT:
- Consider the following pairs of genetic diseases that show Mendelian inheritance. Each of the following pairs represents a genetic disease and it has been matched with a type of inheritance :How many of the pairs given above are correctly matched?
1 Cystic fibrosis Autosomal recessive 2 Huntington's chorea Autosomal dominant 3 Marfan's syndrome Recessive sex-linked Consider the following statements :
Statement I:
Signs of thalassemia major usually develop after 6 months of age.
Statement II:
This is the time when haemoglobin synthesis switches from haemo-globin F to haemoglobin A.
Which one of the following is correct in respect of the above statements?
- Cystic fibrosis involves which of the following organs?
1. Lungs
2. Liver
3. Pancreas
4. Kidney
Select the correct answer using the code given below.
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