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Question

Which of the following statements are correct about the genes? 

(A) Genes are located on chromosomes

 (B) Split genes are composed of exons only 

(C) Genes move from one linkage group to another

 (D) Chromosomes with identical arms on which genes are located are known as isochromosomes

 Choose the correct answer from the options given below:

The correct answer is
(A), (C) and (D) only

Gene Location on Chromosomes

Statement (A) is correct. Genes, the basic units of heredity, are located at specific positions called loci on structures known as chromosomes.

Split Gene Composition

Statement (B) is incorrect. Split genes, found in eukaryotes, are interrupted sequences comprising coding regions called exons and non-coding regions called introns. Both are initially transcribed, but introns are removed later.

Gene Movement Between Linkage Groups

Statement (C) is correct. While genes reside on specific chromosomes (linkage groups), genetic events like translocations can move segments of chromosomes, thereby relocating genes to different linkage groups. Evolutionary processes also lead to changes in gene distribution across chromosomes.

Isochromosome Definition

Statement (D) is correct. Isochromosomes are abnormal chromosomes where one arm (either the p-short arm or the q-long arm) is duplicated, and the other arm is missing. Consequently, both arms are identical.

Summary of Correct Statements

Based on the analysis:

  • (A) Genes are located on chromosomes. (Correct)
  • (B) Split genes are composed of exons only. (Incorrect)
  • (C) Genes move from one linkage group to another. (Correct, via mechanisms like translocation)
  • (D) Chromosomes with identical arms are isochromosomes. (Correct)

Therefore, the correct statements are (A), (C), and (D).

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Important Questions from Molecular Biology

  1. Which of the following removes the RNA primers from the lagging strand?

  2. Action of topoisomerase leads to change in ________.

  3. Consider the options and determine which of the following is not component of yeast artificial chromosome ?

  4. Which of the following amino acids is likely the target for kinase activity?

  5. The movement of a segment of DNA from one site of the genome to another is called

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