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Question

Match the LIST-I with LIST-II

LIST-I
(mRNA marker)
LIST-II
(Body fluid)
A. HBA 1I. Saliva
B. MUC 7II. Menstrual Blood
C. TGM 4III. Blood
D. MMP 7IV. Semen


Choose the correct answer from the options given below:

The correct answer is
A-III, B-I, C-IV, D-II

mRNA Marker and Body Fluid Associations

This solution explains the matching between specific mRNA markers from List-I and their corresponding body fluids from List-II.

A. HBA 1 Marker Association

HBA 1 is the gene for Hemoglobin subunit alpha 1. Hemoglobin is the primary protein found in red blood cells, making Blood the correct association (III).

B. MUC 7 Marker Association

MUC 7 encodes Mucin 7, a major glycoprotein present in human saliva. Thus, the correct match is with Saliva (I).

C. TGM 4 Marker Association

TGM 4 refers to Transglutaminase 4, an enzyme predominantly expressed in the prostate gland and seminal vesicles. It is a significant component of Semen (IV).

D. MMP 7 Marker Association

MMP 7, or Matrix Metalloproteinase 7, is an enzyme found in various tissues and has been identified as a biomarker in specific biological fluids, including Menstrual Blood (II).

Final Matching Summary

By matching each mRNA marker to its primary associated body fluid, we arrive at the correct combination:

  • A. HBA 1 is associated with III. Blood.
  • B. MUC 7 is associated with I. Saliva.
  • C. TGM 4 is associated with IV. Semen.
  • D. MMP 7 is associated with II. Menstrual Blood.

The correct option reflecting this matching is A-III, B-I, C-IV, D-II.

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