Which of the following statements are correct about oral rotavirus vaccines?
I. The storage should be at 2-8°C
II. The vaccine should be used within 2 hours of reconstitution or opening
III. Past history of intussusception is a contraindication
IV. The vaccine can be given if the baby has ongoing diarrhoea
Select the answer using the code given below:
Oral Rotavirus Vaccines Explained
This section analyzes statements about oral rotavirus vaccines to identify correct information regarding their storage, usage, contraindications, and administration during specific health conditions.
Storage of Rotavirus Vaccines
Statement I correctly states that oral rotavirus vaccines require storage at temperatures between 2°C and 8°C. This controlled refrigeration is vital for maintaining the viability and potency of the live attenuated viruses within the vaccine, ensuring its efficacy.
Used Rotavirus Vaccines: Time Limits
Statement II suggests that the vaccine should be used within 2 hours after reconstitution or opening. This is an accurate guideline for many oral vaccines. Exposure to air and environmental factors can degrade the vaccine's stability. Adhering to the specified usage window, such as 2 hours, ensures the administered dose is potent. Always consult product-specific instructions.
Contraindication for Rotavirus Vaccines
Statement III claims that a past history of intussusception is a contraindication. This statement is incorrect. While intussusception is a rare potential risk associated with rotavirus vaccines, a prior history is generally considered a precaution, not an absolute contraindication. Medical professionals evaluate individual risk factors before deciding on vaccination.
Diarrhoea and Rotavirus Vaccines
Statement IV indicates that the vaccine can be administered even if the baby has ongoing diarrhoea. This is correct. Mild to moderate diarrhoea or vomiting does not typically prevent vaccination. The benefits of protection against severe rotavirus disease generally outweigh the risks associated with administering the vaccine during mild gastrointestinal symptoms.
Rotavirus Vaccine Statement Summary
Reviewing the statements:
- Statement I is correct (Storage at 2-8°C).
- Statement II is correct (Used within 2 hours of opening/reconstitution).
- Statement III is incorrect (Past intussusception is a precaution, not absolute contraindication).
- Statement IV is correct (Can be administered with ongoing diarrhoea).
Thus, statements I, II, and IV are correct, aligning with Option C.
Important Questions from Miscellaneous
Which of the following heart sounds are best heard with the bell of stethoscope?
I. Opening snap
II. Systolic click
III. Third heart sound
IV. Mid diastolic murmur
Select the correct answer using the code given below:Consider the following statements for diagnosing ventricular aneurysm in a patient with recent myocardial infarction:
I. Paradoxical impulse on chest wall
II. Persistent ST elevation on ECG
III. Unusual bulge from cardiac silhouette on X-ray
IV. Presence of pulsus paradoxsus
Which of the above are correct?Which one of the following statements is correct for subcutaneous nodules in Rheumatic fever?
Which one of the following is correct with regard to Carey Coombs murmur?
Which of the following statements is correct regarding the Opening Snap (OS) in a patient of mitral stenosis?
