Question
Which of the following pharmacological agents can be used for the treatment of visceral Leishmaniasis? 1. Pentavalent antimonials 2. Amphotericin B 3. Spiramycin 4. Paromomycin Select the correct answer using the code given below:
The correct answer is
1, 2 and 4
Visceral Leishmaniasis Treatment Agents Explained
The question asks to identify pharmacological agents effective against visceral leishmaniasis.
Effective Treatment Agents
The following agents are recognized for treating visceral leishmaniasis:
- 1. Pentavalent antimonials: These (like sodium stibogluconate and meglumine antimoniate) are traditionally first-line treatments in many regions.
- 2. Amphotericin B: Particularly liposomal formulations, Amphotericin B is a crucial and effective treatment, often used for resistant cases.
- 4. Paromomycin: This aminoglycoside antibiotic has shown efficacy in treating visceral leishmaniasis, sometimes used in combination regimens.
Ineffective Treatment Agent
The agent listed that is generally NOT used for visceral leishmaniasis is:
- 3. Spiramycin: While a macrolide antibiotic, Spiramycin is primarily used for other infections (like toxoplasmosis) and lacks efficacy for visceral leishmaniasis.
Conclusion
Based on the established treatments, the correct combination includes Pentavalent antimonials (1), Amphotericin B (2), and Paromomycin (4). Therefore, the correct option is the one that lists 1, 2, and 4.
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Important Questions from Protozoal Infections
- Which one of the following has the maximum diagnostic sensitivity for Leishmaniasis?
- Which one of the following statements regarding cryptosporidiosis is NOT correct?
- Which one of the following diseases is NOT caused by protozoa?
- Bite of the Tsetse Fly transmits:
- Infection with which of the following organisms can cause a syndrome which is clinically indistinguishable from achalasia of the oesophagus?
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