All Exams Test series for 1 year @ ₹349 only
Question

Which of the following is NOT a maternal risk factor for the development of a neural tube defect?

The correct answer is
Intake of Phenytoin

The question asks to identify which option is NOT a maternal risk factor for developing neural tube defects (NTDs).

Neural Tube Defect Maternal Risks

Neural tube defects are birth defects affecting the brain and spine. Certain maternal factors significantly increase the risk of their development during pregnancy.

Established Maternal Risks Identified

Several factors are known to increase the risk of NTDs:

  • Insulin dependent Diabetes Mellitus: Uncontrolled maternal diabetes is a significant risk factor, as high blood glucose levels can interfere with embryonic development.
  • Exposure to radiation: High levels of ionizing radiation are teratogenic and can cause developmental abnormalities, including NTDs.
  • Folate deficiency: Folic acid (Vitamin B9) is crucial for neural tube closure. Insufficient folate levels in early pregnancy are a primary cause of NTDs.

Identifying the Non-Risk Factor

Based on established medical knowledge, Insulin dependent Diabetes Mellitus, Exposure to radiation, and Folate deficiency are recognized maternal risk factors for NTDs.

Therefore, among the choices provided, Intake of Phenytoin is identified as the correct answer, representing the option that is NOT considered a maternal risk factor in this specific context.

Was this answer helpful?

Important Questions from Congenital Disorders

  1. Trisomy 13 is also known as:
  2. Which one of the following is a type of glycogen storage disease?
  3. Which of the following biochemical tests for the detection of aneuploidies is performed in the first trimester of pregnancy?

  4. Which of the following is NOT a birth defect related to a disorder in the development of the whole eyeball?

  5. Which of the following types of tracheoesophageal fistulae is the most common?
Need Expert Advice?

Start Your Preparation with Prepp Mobile App

Download the app from Google Play & App Store
Download the app from Google Play & App Store
Prepp Mobile App