1. Peripheral entrapment neuropathies
2. Subluxation of the cervical spine at the atlanto-axial joint
3. Primary amyloidosis
4. Lymphoma
Select the correct answer using the code given below:
Rheumatoid Arthritis Complications Explained
This question asks to identify the complications associated with Rheumatoid Arthritis (RA). RA is a chronic autoimmune disease primarily affecting joints, but it can also lead to systemic complications.
Evaluating Potential Complications
Let's examine each listed item:
- 1. Peripheral entrapment neuropathies: RA commonly causes inflammation and swelling around joints and nerves. This can compress nerves, leading to conditions like carpal tunnel syndrome, which is a type of peripheral entrapment neuropathy. This is a recognized complication.
- 2. Subluxation of the cervical spine at the atlanto-axial joint: Inflammation in RA can affect the ligaments and bones of the upper cervical spine, specifically the C1 (atlas) and C2 (axis) vertebrae. This can lead to instability and subluxation (partial dislocation), posing a risk of spinal cord compression. This is a known complication.
- 3. Primary amyloidosis: While chronic inflammation in RA can sometimes lead to secondary amyloidosis (AA type), primary amyloidosis (AL type) is not typically considered a direct complication of RA itself.
- 4. Lymphoma: Patients with RA have an increased risk of developing certain types of lymphoma, particularly non-Hodgkin lymphoma. This association is linked to chronic inflammation and potentially some RA treatments. This is a recognized complication.
Conclusion on RA Complications
Based on the analysis, peripheral entrapment neuropathies (1), subluxation of the cervical spine (2), and lymphoma (4) are established complications of Rheumatoid Arthritis. Primary amyloidosis is less directly associated.
Therefore, the correct combination is 1, 2, and 4.
Important Questions from Arthritis
- Which of the following statements regarding Ankylosing spondylitis (AS) are true?
1. AS occurs in about 10 % of Inflammatory Bowel Disease(IBD) patients
2. The AS activity is related to Bowel activity in IBD patients
3. The AS activity does remit with glucocorticoids or colectomy in IBD patients
Select the correct answer using the code given below: - Which of the following statements about “Early onset Osteoarthritis” are true?
1. Onset is usually before the age of 55 years
2. There is clear history of previous trauma
3. In most cases, single joint is affected
Select the correct answer using the code given below: - A 31-year young man presents with fever, weight loss, pain with swelling of knee joint and low backache with stiffness. Three weeks earlier, he was treated for symptoms of urinary tract infection by local practitioner. The joint aspirate is leucocyte rich and contains multinucleated macrophages. His urine culture is sterile. What is the most probable diagnosis?
- Consider the following statements regarding Gout in old age.
1. Most of older patients have gout secondary to diuretic use and chronic kidney disease
2. Joints of the upper limbs are more frequently affected
3. Presentation is typical with acute attack of gout
Which of the statements given above are correct? - A 28-year old woman complains of arthritis involving bilateral metacarpophalangeal, proximal interphalangeal and wrist joints of one year duration. The most likely disease entity is:
