Question
Which of the following are correct with regard to Ankylosing spondylitis ?
1. Bamboo spine may be seen
2. Early morning back pain is rare
3. Uveitis is most common extra articular feature
4. It is more common in males
Select the correct answer using the code given below :
The correct answer is
1, 3 and 4
Ankylosing Spondylitis: Key Features
Ankylosing Spondylitis (AS) is a chronic inflammatory seronegative spondyloarthropathy that primarily affects the sacroiliac joints and axial skeleton. The correct answer is 1, 3 and 4.
Statement Analysis
- Statement 1: Bamboo spine may be seen — Correct. In advanced/late-stage disease, progressive syndesmophyte formation with ossification of the annulus fibrosus and paravertebral ligaments fuses adjacent vertebrae, producing the classic "bamboo spine" appearance on spinal X-ray.
- Statement 2: Early morning back pain is rare — Incorrect. Inflammatory back pain is a hallmark of AS, and it characteristically presents with prominent early morning stiffness and pain that improves with activity/exercise and worsens with rest — the opposite of what this statement claims. Early morning back pain is common, not rare, in AS.
- Statement 3: Uveitis is the most common extra-articular feature — Correct. Acute anterior uveitis (iritis) is the most frequent extra-articular manifestation of Ankylosing Spondylitis, occurring in roughly 25–40% of patients, often as recurrent, unilateral, painful red eye episodes. It is more common than cardiac (aortic regurgitation, conduction defects) or pulmonary (apical fibrosis) involvement.
- Statement 4: It is more common in males — Correct. AS shows a strong male predominance, with a male-to-female ratio classically cited around 3:1 (though milder/atypical disease is increasingly recognized in females).
Conclusion
Statements 1, 3, and 4 are true, while statement 2 is false because morning back stiffness/pain is a defining and common feature of AS rather than a rare one. Hence, the correct option is "1, 3 and 4".
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Important Questions from Arthritis
- Which of the following statements regarding Ankylosing spondylitis (AS) are true?
1. AS occurs in about 10 % of Inflammatory Bowel Disease(IBD) patients
2. The AS activity is related to Bowel activity in IBD patients
3. The AS activity does remit with glucocorticoids or colectomy in IBD patients
Select the correct answer using the code given below: - Which of the following statements about “Early onset Osteoarthritis” are true?
1. Onset is usually before the age of 55 years
2. There is clear history of previous trauma
3. In most cases, single joint is affected
Select the correct answer using the code given below: - A 31-year young man presents with fever, weight loss, pain with swelling of knee joint and low backache with stiffness. Three weeks earlier, he was treated for symptoms of urinary tract infection by local practitioner. The joint aspirate is leucocyte rich and contains multinucleated macrophages. His urine culture is sterile. What is the most probable diagnosis?
- Consider the following statements regarding Gout in old age.
1. Most of older patients have gout secondary to diuretic use and chronic kidney disease
2. Joints of the upper limbs are more frequently affected
3. Presentation is typical with acute attack of gout
Which of the statements given above are correct? - A 28-year old woman complains of arthritis involving bilateral metacarpophalangeal, proximal interphalangeal and wrist joints of one year duration. The most likely disease entity is:
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