Question
What is correct sequence of elimination half life of following calcium channel blockers in increasing order
A. Felodipine
B. Isradipine
C. Clevidipine
D. Amlodipine
Choose the correct answer from the options given below:
This question was previously asked in
CUET PG 2026 Agri-Business Management Question Paper (25-Mar-2026) (Shift 2)
The correct answer is
C, B, A, D
Calcium Channel Blocker Elimination Half-Life Order
This section details the correct sequence of elimination half-life for specific calcium channel blockers in increasing order.
Understanding Elimination Half-Life
The elimination half-life ($t_{1/2}$) represents the time taken for the drug concentration in the body to reduce by half. It is essential for determining appropriate drug dosages and administration intervals.
Drug Half-Life Data
Comparing the approximate elimination half-lives ($t_{1/2}$) for the drugs listed:
| Drug Name | Question Abbreviation | Approx. Half-Life ($t_{1/2}$) |
| Felodipine | A | Approximately 15 hours |
| Isradipine | B | Approximately 8 hours |
| Clevidipine | C | Approximately 9 minutes |
| Amlodipine | D | Approximately 40 hours |
Determining the Sequence
Ordering these calcium channel blockers by their elimination half-life, from shortest to longest:
- Clevidipine (C): ~ 9 minutes (Shortest)
- Isradipine (B): ~ 8 hours
- Felodipine (A): ~ 15 hours
- Amlodipine (D): ~ 40 hours (Longest)
The correct sequence using the question's abbreviations is C, B, A, D.
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